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Clinical research is based on the parameters at defined time points, such as admission, diagnosis or discharge, for the purpose of risk factor analysis in relation to outcome. However, these parameters are col...
Wound healing in diabetic patients is mainly hindered by a combination of long-term glycosylation, persistent inflammatory response, and immunosuppressive state. The interaction of these factors not only resul...
To identify the risk factors of bacterial blood stream infection (BSI) and construct a nomogram to predict the occurrence of bacterial BSI.
Sepsis-induced lung injury is a serious complication that contributes to the high morbidity and mortality rates in septic patients. This study aims to identify genes associated with sepsis-induced lung injury ...
Notch signaling is a widely preserved communication pathway that supports essential cellular functions by allowing adjacent cells to interact. The Notch signaling pathway consists of Notch ligands (DSL protein...
Hypervolemia is associated with worse outcomes in critically ill patients with acute respiratory distress syndrome (ARDS), with early positive fluid balance linked to longer intensive care unit (ICU) stays, pr...
To analyze the clinical features and prognosis of migraine with PFO and explore their short-term prognostic factors.
Neuromyelitis Optica Spectrum Disorder (NMOSD) affects the optic nerves and spinal cord, but its longitudinal effects on brain function remain unclear. This study aims to examine changes in brain functional co...
Sleep disturbances (SD) exhibit a high prevalence among older adults and exert considerable influence on cardiovascular health, quality of life, and other facets of well-being. α-Klotho, an anti-aging factor t...
In this retrospective study, we investigated the changes in choroidal thickness (CT) using enhanced depth imaging spectral domain–optical coherence tomography (EDI–OCT) and intraocular pressure (IOP) following...
This retrospective cohort study aims to compare perioperative outcomes between laparoscopic and open surgical repair of obturator hernia, a rare but clinically significant abdominal wall hernia.
Inflammation is a complex, tightly regulated process involving biochemical and cellular reactions to harmful stimuli. Often termed “the internal fire”, it is crucial for protecting the body and facilitating ti...
Pulmonary fibrosis (PF) is a disease characterized by dysregulated extracellular matrix deposition and aberrant fibroblast activation. Emerging evidence implicates that dysregulated copper metabolism contribut...
Tumor angiogenesis facilitates cancer progression by supporting tumor growth and metastasis. MicroRNA-155 (miR-155) plays a pivotal role in regulating angiogenesis through both direct effects on tumor and endo...
The study analyzed the relationship between serum levels of HMGB1 and biochemical indices related to atherosclerosis, clarifying the diagnostic value of HMGB1 in cases of myeloproliferative neoplasm (MPN) acco...
Radiofrequency ablation (RFA) and cryoablation are minimally invasive treatments for renal cell carcinoma (RCC). However, their comparative efficacy remains under evaluation. This study aims to compare overall...
Retrograde venous perfusion (RVP) is a minimally invasive procedure in which the limb circulation is isolated by the application of a proximal limb tourniquet, followed by the administration of specific medica...
To investigate the relationship between crystalline lens thickness (LT) and subtypes of intermittent exotropia (IXT) in children, focusing on ocular biometry and accommodation characteristics.
This study aimed to develop and evaluate the effectiveness of a perioperative blood management plan based on the problem, intervention, control, and outcomes (PICO) model for long-segment lumbar spine posterio...
Transthoracic echocardiography can be performed under sedation in children with Down syndrome who have neurological or behavioral problems. This study aimed to compare the efficacy and safety of intranasal dex...
Artificial intelligence (AI), with its technologies such as machine perception, robotics, natural language processing, expert systems, and machine learning (ML) with its subset deep learning, have transformed ...
The proportion of elderly patients undergoing Total knee arthroplasty (TKA) is growing. Optimizing and accelerating postoperative recovery for TKA patients is critical in clinical practice. Enhanced Recovery A...
A critical measure to reduce the risk of ipsilateral breast tumor recurrence after breast-conserving surgery (BCS) for patients with early invasive breast cancer (BC) is ensuring negative margins through froze...
Renal perfusion pressure plays a crucial role in the pathophysiology of acute kidney injury (AKI). While multiple methods are available for calculating renal perfusion pressure, the optimal calculation approac...
Artificial intelligence (AI) has transformed healthcare, particularly in robot-assisted surgery, rehabilitation, medical imaging and diagnostics, virtual patient care, medical research and drug discovery, pati...
To explore the effects of pelvic floor muscle (PFM) combined with pulmonary rehabilitation training on diaphragm function and lung function in elderly patients with intertrochanteric fracture.
The search for effective drugs that promote regeneration after peripheral nerve injury (PNI) has received widespread attention, but little attention has been paid to the potential secondary damage to nerves du...
The purpose of this review is to compare the effectiveness of SuperPulsed thulium fiber laser (SP TFL) and holmium:yttrium–aluminum–garnet (Ho:YAG) laser in lithotripsy, with the aim of evaluating the differen...
Recently, invisible appliances have become popular due to their aesthetics and comfort, but their impact on periodontal health in periodontitis patients has not been fully elucidated. The purpose of this study...
Traffic accidents worldwide are considered a public health problem and traumatic injuries due to the phenomenon of whiplash with clinical manifestations such as neck or head pain and temporomandibular joint pa...
To investigate the causative factors, antimicrobial resistance patterns, and associated risk factors of postoperative incisional infections in patients with acute intestinal obstruction and to develop a predic...
Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening disease with high morbidity and mortality. The triglyceride–glucose (TyG) index, a marker of insulin resistance (IR), has been linked to adverse ...
The study aimed to assess the prognostic impact of lymph node (LN) metastasis combined with surgical margin status on the 5-year overall survival (OS) of patients after radical resection perihilar cholangiocar...
Effective biomarkers for esophageal carcinoma (ESCA) are currently lacking. Here, we examined the role of minichromosome maintenance complex component 8 (MCM8) as a diagnostic and prognostic marker in ESCA and...
The prediction of mortality for elderly patients undergoing non-cardiac surgeries is a vital research area, as accurate risk assessment can help surgeons make better clinical decisions during the perioperative...
Interdisciplinary trauma patients with multiple injuries require special attention from the first minute of care. This study aimed to determine the overall injury distribution in patients with head and neck in...
Bariatric surgery is currently considered the key treatment method for patients with obesity and related complications. Among the various surgeries, laparoscopic sleeve gastrectomy (LSG) is the most widely use...
Estrogen-related receptor β (ERRβ) alternative splicing isoforms, including ERRβsf, ERRβ2, and ERRβΔ10, have been implicated in the pathogenesis of malignant tumors. Nevertheless, their specific impact on esop...
Gastric cancer in young (GCY) is increasing in incidence with poor prognosis. Current screening and molecular methods are inadequate, necessitating new approaches to explore its pathogenesis. This study used s...
The risk factors associated with postoperative complications following pulmonary resection in individuals with tuberculosis remain incompletely understood.
We carried out a study to assess the efficacy of tranexamic acid in preventing scar tissue in the craniectomy area in rats.
Chronic alcohol-related brain damage (ARBD) is mainly manifested as learning and memory impairment and cognitive decline in the long term. Ca2+ plays a key role in learning and memory impairment. The increase of ...
Attention plays a vital part in the cognitive process, where different kinds of attention are associated with separate brain mechanisms. The objective of this research was to investigate the patterns of brain ...
Atherosclerosis of aortic wall has been suggested as a key pathological feature of abdominal aortic aneurysm (AAA). We conducted a first-ever prospective cohort study aiming at assessing the sex-specific assoc...
This scoping review aims to synthesize evidence regarding the neural mechanisms and pathways underlying postoperative nausea and vomiting (PONV). We systematically searched the PubMed, Embase and Cochrane Libr...
A retrospective cohort study.
Hyperuricemia may be one of the risk factors for the development of prostate cancer. We evaluated the association between serum uric acid (SUA) and elevated prostate-specific antigen (PSA) in the middle-aged a...
Atherosclerosis (AS), a chronic inflammatory disease of the arterial wall, remains a dominant cause of death and disability globally. Quercetin has been evidenced to be effective against AS, but the exact mech...
This study aimed to develop and validate an explainable machine learning (ML) model to predict 28-day all-cause mortality in immunocompromised patients admitted to the intensive care unit (ICU). Accurate and i...
This study developed a nomogram to predict the risk of ischemic mitral regurgitation (IMR) after percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) pat...
Citation Impact 2023
Journal Impact Factor: 2.8
5-year Journal Impact Factor: 2.9
Source Normalized Impact per Paper (SNIP): 0.818
SCImago Journal Rank (SJR): 0.736
Speed 2024
Submission to first editorial decision (median days): 10
Submission to acceptance (median days): 129
Usage 2024
Downloads: 2,400,811
Altmetric mentions: 2,214