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This preliminary study explores the prognostic value of pretreatment peripheral serum apolipoprotein E (ApoE) in patients with non-metastatic nasopharyngeal carcinoma (NPC).
Heat stroke (HS) is a critical medical emergency characterized by severe hyperthermia and central nervous system dysfunction, occurring predominantly in conditions of high ambient temperatures or through physi...
The trunk muscles play an important role in generating motion and maintaining posture stability. We aimed to investigate the sex-dependent differences in the three-dimensional isometric and isokinetic trunk mu...
This study aimed to assess the efficacy and complications of one-stage posterior hemivertebrectomy and asymmetric osteotomy combined with posterior release in treating congenital scoliosis among young children.
This is a cross-sectional study.
Lung cancer is the most widespread and fatal oncological disease, with lung adenocarcinoma (LUAD) being the predominant subtype, characterized by a poor long-term survival rate. Although the N7-methylguanosone...
Prostate cancer (PCa) is a serious malignancy worldwide with the fifth highest mortality rate among tumors in males, and there are unmet clinical needs for PCa treatment. In this work, we aim to explore the ex...
It is crucial to identify the risk factors for unplanned extubation (UEX) in thoracoabdominal drainage tubes as early as possible and establish applicable risk prediction model to reduce the incidence of UEX.
Thrombocytopenia is a common manifestation of antiphospholipid syndrome (APS). This study assesses the possible relationship between severe thrombocytopenia and adverse pregnancy outcomes (APOs) in obstetric A...
A single-center retrospective study was conducted to investigate whether the prophylactic application of a single-use negative pressure wound therapy (sNPWT) dressing on closed surgical incisions following inc...
Thromboangiitis obliterans (TAO) is characterized by progressive inflammatory vasculopathy featuring thrombotic occlusion. Aberrant thrombosis induces endothelial damage through pathological clotting, while ir...
Emerging evidence has revealed the potential efficacy of Novel Hormonal Agent (NHA) or chemotherapy in high-risk patients with biochemical recurrence (BCR). However, the optimal drug-based treatment strategy r...
This study aims to investigate the correlation between different modes of physical activity (PA) and sleep health.
The aim of this study was to investigate the impact of training prior to music therapy-assisted childbirth on labor pain and delivery outcomes in parturients.
Kidney-Yang Deficiency Syndrome (KYDS) is associated with lipid metabolism dysregulation. This study aimed to investigate the effect of casitas B-lineage lymphoma (CBL)-mediated aquaporin 1 (AQP1) ubiquitinati...
AlkB homolog (ALKBH) belongs to 2-oxoglutarate (2OG) and ferrous iron-dependent oxygenases, which can catalyze the demethylation of DNA/RNA and play an important role in human diseases represented by cancer. A...
This study aims to investigate the application strategy of “single point—point pressure method” and multi-point injection techniques for carbon nanoparticle injection in laparoscopic radical resection of recta...
Patients with dysphagia due to nasopharyngeal carcinoma (NPC) after radiotherapy often have chewing difficulty. Kinematic analysis of mandibular movements may provide clinically useful information for the chew...
Acute lung injury (ALI) induced by aspiration of gastric acid is a complex and serious disease with high morbidity and mortality, and the lack of sensitive biomarkers hampers the timely treatment. This study a...
Interleukin 6 receptor (IL6R) inhibitors are effective drugs as therapy for rheumatoid arthritis (RA). However, few studies on IL6R inhibition for relieving chronic low back pain (CLBP) have been conducted. Th...
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe disorders affecting the skin and mucous membranes, identified by low incidence but high mortality rates. Medications, particularly...
This study was to investigate the effects of freeze-dried powder of lactic acid bacteria treatment of pediatric bacterial peritonitis on immune function and nutritional status.
Compared the impact of ultrasound contrast-enhanced fusion virtual navigation technology-guided microwave ablation (MWA) and standard MWA on the local tumor progression of hepatocellular carcinoma with unclear...
Type 2 diabetes mellitus (T2DM) is a complex metabolic disease involving multiple pathophysiological mechanisms, such as insulin resistance and β-cell dysfunction. Recently, the emergence of precision medicine...
To investigate the risk factors associated with postoperative hypercoagulability in patients undergoing total knee arthroplasty (TKA), and subsequently develop a predictive model to facilitate early decision-m...
The gut microbiota plays a substantial role in obesity. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) can affect body weight, insulin resistance, and lipid metabolism via combined hypothalamic feeding c...
Sleep disorders may impair the nervous and immune systems. In thyroid eye disease (TED), an autoimmune condition, sleep quality and its potential determinants remain unclear. The study aimed to assess the slee...
Leptospirosis is a zoonosis of global importance with a wide array of clinical outcomes. The clinical course of leptospirosis varies from an undifferentiated mild febrile illness to multiorgan dysfunction and ...
Metabolic inflammatory syndrome (MIS) is a novel concept in integrative healthcare that focuses on addressing metabolic disorders. The systemic immune-inflammatory index (SII) and systemic inflammatory respons...
Myocardial infarction with nonobstructive coronary arteries (MINOCA) refers to myocardial infarction cases with less than 50% narrowing of coronary arteries, accounting for about 2% to 10% of acute myocardial ...
While percutaneous coronary intervention (PCI) has improved survival rates, many patients remain at risk for future adverse cardio-cerebral events. This study explores the role of insulin resistance, measured ...
Magnetic nanoparticles (MNPs) have emerged as powerful tools in biomedicine due to their distinct physicochemical characteristics, including a high surface-area-to-volume ratio, adjustable size, magnetic sensi...
Reduction mammaplasty (RM) is a commonly performed plastic surgery procedure, but various postoperative complications have been noted. This study aims to identify and quantify the association between risk fact...
To elucidate the potential targets and mechanisms of Brucea javanica in the treatment of oral squamous cell carcinoma (OSCC) through network pharmacology and molecular docking, supported by clinical data and in v...
Distraction osteogenesis (DO) is a highly effective method for bone regeneration. However, its prolonged treatment duration limits its clinical application. Parathyroid hormone (PTH) can promote distraction os...
Bone defects seriously affect patients' quality of life and are difficult to repair, and the use of biodegradable porous scaffolds for bone defect repair has gradually become a hot spot in the field of bone re...
The relationship between the neutrophil-monocyte-to-lymphocyte ratio (NMLR) and adverse outcomes in patients with chronic kidney disease (CKD) and type 2 diabetes remains unclear. This study explored the assoc...
Cuproptosis is a brand-new copper-dependent type of cell death that has been linked to various tumors. However, the relationship between cuproptosis and acute lymphoblastic leukemia (ALL) remains to be further...
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline, behavioral impairments, and psychiatric comorbidities. The pathogenesis of AD remains incompletely eluci...
It is noted that postoperative acute kidney injury (AKI) in neonates is known to be associated with adverse outcomes, yet its incidence and risk factors remain incompletely elucidated. The current study aims t...
To investigate the association between Hemodialysis (HD) and postoperative outcomes in patients diagnosed with chronic renal failure (CRF) who underwent pars plana vitrectomy (PPV) for proliferative diabetic r...
The ratio between erythrocyte distribution width and serum albumin (RAR) has gained recognition as a novel composite biomarker for inflammatory processes, though its clinical significance in Parkinson's diseas...
The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is a recently developed lipid parameter, but there are insufficient studies exploring its relationship with ear...
Diabetes mellitus (DM) is a metabolic disease with complex pathogenic mechanisms. Histone deacetylase 4 (HDAC4) is a member of an important family of epigenetic modifications. An increasing amount of research ...
This study investigates the association between urolithiasis-induced hydronephrosis and the reactivation of herpes zoster (HZ).
Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) is widely used for the treatment of femoral neck fractures.
To evaluate changes in retinal layer thickness and microvascular density in pancreatitis patients using optical coherence tomography angiography (OCTA).
Glioma is still one of the most aggressive and common types of brain and central nervous system cancer, with few effective treatment options. Despite progress in therapy, there is a requirement for new methods...
Dilated cardiomyopathy (DCM) is a prevalent etiology of heart failure, distinguished by the gradual and frequently irreversible myocardial muscle impairment. Roughly 50% of DCM occurrences stem from hereditary...
Citation Impact 2023
Journal Impact Factor: 2.8
5-year Journal Impact Factor: 2.9
Source Normalized Impact per Paper (SNIP): 0.818
SCImago Journal Rank (SJR): 0.736
Speed 2024
Submission to first editorial decision (median days): 10
Submission to acceptance (median days): 129
Usage 2024
Downloads: 2,400,811
Altmetric mentions: 2,214