Skip to main content

Table 3 Uni- and multivariate Cox regression analysis for overall survival in patients with lymph node metastasis

From: Prognostic impact of lymph node and surgical margin in patients with perihilar cholangiocarcinoma

Variables

n

Survival Rate (%)

Univariate P

Multivariate

3-year

5-year

HR (95%CI)

P

Age

  < 65

18

58.5

41.8

0.969

  

  ≥ 65

14

55.0

27.5

 

Sex

 Male

20

51.3

36.7

0.676

  

 Female

12

65.6

49.2

 

PBD

 Yes

29

53.5

40.8

0.901

  

 No

3

66.7

33.3

 

Combined PD

 Absent

30

57.3

38.2

0.813

  

 Present

2

50.0

50.0

 

Combined PV and/or HA

 Absent

23

67.5

52.5

0.033

  

 Present

9

29.6

 

Blood transfusion

 Absent

6

80.0

53.3

0.376

  

 Present

26

52.0

36.4

 

Bismuth classification

 Type I-III

20

67.8

47.5

0.192

  

 Type IV

12

41.7

27.8

 

Differentiation grade

 Moderate/well

22

69.8

54.3

0.004

1

0.007

 Poor

10

26.7

13.3

3.930 (1.446–10.679)

Microscopic perineural invasion

 Absent

23

66.0

45.3

0.080

  

 Present

9

33.3

 

Microscopic perineural invasion

 Absent

2

0.950

  

 Present

30

54.1

41.7

 

R

 0

24

64.0

42.7

0.185

  

 1/2

8

33.3

 
  1. PBD preoperative biliary drainage, PD pancreaticoduodenectomy, PV portal vein, HA hepatic artery, CI confidence intervals, HR hazard ratio