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Table 1 Patients’ baseline characteristics

From: Sedation for transthoracic echocardiography in children with Down syndrome: a propensity score-weighted retrospective cohort study

Variables

Unweighted study population

Weighted study population

All cohort (n = 149)

Chloral hydrate group (n = 75)

Dexmedetomidine group (n = 74)

Statistic

p Value

SMD

All cohort (n = 298)

Chloral hydrate group (n = 150)

Dexmedetomidine group (n = 148)

Statistic

p Value

SMD

Age (months)

14 [8–24]

11 [7–22]

16.5 [9–24]

2.21

0.027

0.11

15 [8–24]

12 [7–24]

16 [9–24]

− 0.41

0.6794

0.03

Weight (kg)

8 [6.5–11]

7 [6–10]

9 [7–11]

1.69

0.09

0.15

8 [6.5–11]

7.5 [6–11]

9 [6.6–11]

0.93

0.3534

0.03

Sex

Male

73 (49)

36 (48)

37 (50)

0.06

0.8071

0.04

147 (49.3)

74 (49.4)

73 (49.3)

0.00

0.981

 < 0.01

Female

76 (51)

39 (52)

37 (50)

   

151 (50.7)

76 (50.6)

75 (50.7)

   

Type of CHD

Simple cases

84 (56.4)

43 (57.3)

41 (55.4)

0.06

0.8125

0.04

167 (55.9)

84 (55.8)

83 (56)

0.00

0.9726

 < 0.01

Complex cases

65 (43.6)

32 (42.7)

33 (44.6)

   

131 (44.1)

66 (44.2)

65 (44)

   

Fasting time

 ≤ 3 h

91 (61.1)

44 (58.7)

47 (63.5)

0.37

0.5441

0.1

182 (61.1)

91 (61)

91 (61.3)

0.00

0.9477

0.01

 > 3 h

58 (38.9)

31 (41.3)

27 (36.5)

   

116 (38.9)

58 (39)

57 (38.7)

   
  1. Data are expressed as median [interquartile range] (for continuous variables) and n (%) (for categorical variables). SMD, standardized mean difference; CHD, congenital heart disease