Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Fig. 5 | European Journal of Medical Research

Fig. 5

From: Tetrathiomolybdate alleviates bleomycin-induced pulmonary fibrosis by reducing copper concentration and suppressing EMT

Fig. 5

TTM reverses TGF-β-induced epithelial–mesenchymal transition (EMT) and fibroblast-to-myofibroblast transition (FMT). A, B RT-PCR analysis showing Vimentin and E-cadherin mRNA levels in epithelial cells (Beas-2b cells) across three groups: control (CT), treated with TGF-β (TGF) (10 ng/mL) and TGF-β with TTM (TGF&TTM) for 48 h. C Western blot analysis of Vimentin and E-cadherin expression in Beas-2b cells for the CT, TGF and TGF&TTM groups. Quantitative analysis of protein band intensities is shown in an accompanying bar graph. D, E RT-PCR analysis showing α-SMA and Col1 A1 mRNA levels in in fibroblast cells (MRC-5) across three groups. F Western blot analysis of α-SMA and Col1 A1expression in fibroblast cells (MRC-5) for the CT, TGF and TGF&TTM groups. Quantitative analysis of protein band intensities is shown in an accompanying bar graph. Data are presented as mean ± SD.*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 (one-way ANOVA) in this figure

Back to article page

European Journal of Medical Research

ISSN: 2047-783X

Contact us