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Table 2 Univariate and multivariate Cox regression analysis for prognostic factors of patients with ESCC

From: Expression and prognostic value of estrogen-related receptor β alternative splicing isoforms in esophageal squamous cell carcinoma

Characteristic

Univariate analysis

Multivariate analysis

HR

95% CI

P-value

HR

95% CI

P-value

Age (year)

 ≤ 70

Ref

    

 > 70

0.955

0.312–2.927

0.936

   

Sex

 Male

Ref

    

 Female

0.739

0.203–2.688

0.646

   

Tumor length (cm)

 ≤ 3

Ref

    

 3–5

1.129

0.364–3.504

0.834

   

 ≥ 5

0.396

0.048–3.287

0.391

   

G stage

 G1

Ref

    

 G2

1.284

0.385–4.289

0.684

   

 G3

0.803

0.089–7.228

0.845

   

T stage

 T1

Ref

    

 T2

0.145

0.013–1.607

0.115

   

 T3

0.745

0.162–3.421

0.705

   

N stage

 N0

Ref

    

 N1

1.467

0.447–4.821

0.528

1.181

0.355–3.930

0.768

 N2–3

4.323

0.843–22.185

0.079*

7.892

1.328–46.911

0.023**

pTNM stage

 I

Ref

    

 II

1.522

0.181–13.321

0.689

   

 III–IV

2.897

0.354–23.697

0.321

   

ERRβsf/ERRβ

 Low

Ref

 

Ref

 

 High

0.302

0.100–0.910

0.033**

0.219

0.063–0.767

0.018**

  1. Only variables with a P < 0.1 in the univariate analysis were included as covariates for the multivariate analysis
  2. ESCC: esophageal squamous cell carcinoma; y: year; HR: hazard ratio; CI: confidence interval; Ref: reference
  3. *P < 0.1
  4. **P < 0.05
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European Journal of Medical Research

ISSN: 2047-783X

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