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Table 2 Comparative efficacy of PONV prevention strategies [1, 33, 41]

From: The neural mechanism and pathways underlying postoperative nausea and vomiting: a comprehensive review

Intervention strategy

RRR (%)

NNT

Common adverse reactions

Level of evidence

5-HT3 antagonist

25–30

4–5

Headache, constipation

Ia (Cochrane)

Dexamethasone

20–25

5–6

High blood sugar and insomnia

Ia

Acupressure (PC6)

15–20

6–8

Local skin irritation

Ib(RCT)

Isopropanol infusion

30–35

3–4

Hypotension, injection pain

Ia