Table 1 Univariate analysis of initial margin positivity in intraoperative frozen section during BCS
Factors | Initial negative margins | Initial positive margins | Ļ2 | P |
|---|---|---|---|---|
Age | 0.005 | 0.942 | ||
ā¦35 years | 50 (16.0%) | 20 (16.3%) | ||
> 35 years | 263 (84.0%) | 103 (83.7%) | ||
Menopause | 3.098 | 0.078 | ||
No | 235 (75.1%) | 102 (82.9%) | ||
Yes | 78 (24.9%) | 21 (17.1%) | ||
Pathological nipple discharge | 3.022 | 0.082 | ||
No | 289 (92.3%) | 107 (87.0%) | ||
Yes | 24 (7.7%) | 16 (13.0%) | ||
Tumor diameter | 6.279 | 0.012 | ||
ā¤ 3 cm | 293 (93.6%) | 106 (86.2%) | ||
ā> 3 cm | 20 (6.4%) | 17 (13.8%) | ||
Distance from the tumor to the nipple | 5.395 | 0.020 | ||
ā > 2 cm | 186 (59.4%) | 58 (47.2%) | ||
ā¤ 2 cm | 127 (40.6%) | 65 (52.8%) | ||
Calcification | 0.014 | 0.906 | ||
Calcification | 57 (18.2%) | 23 (18.7%) | ||
No calcification | 256 (81.8%) | 100 (81.3%) | ||
Preoperative breast MRI | 0.163 | 0.686 | ||
No | 56 (17.9%) | 20 (16.3%) | ||
Yes | 257 (82.1%) | 103 (83.7%) | ||
Pathology | 0.817 | 0.366 | ||
Intraductal carcinoma | 46 (14.7%) | 14 (11.4%) | ||
Invasive carcinoma | 267 (85.3%) | 109 (88.6%) | ||
Histological grade | 0.002 | 0.961 | ||
IāII | 288 (92.0%) | 113 (91.9%) | ||
III | 25 (8.0%) | 10 (8.1%) | ||
ER status | 1.029 | 0.310 | ||
Positive | 246 (78.6%) | 102 (82.9%) | ||
Negative | 67 (21.3%) | 21 (17.1%) | ||
Her-2 status | 0.025 | 0.874 | ||
Positive | 59(18.8%) | 24 (19.5%) | ||
Negative | 254 (81.2%) | 99 (80.5%) | ||
Ki-67 | 0.528 | 0.468 | ||
ā¤ 30% | 190 (60.7%) | 70 (56.9%) | ||
ā> 30% | 123 (39.3%) | 53 (43.1%) | ||
Axillary lymph node | 3.942 | 0.047 | ||
Negative | 258 (82.4%) | 91 (74.0%) | ||
Positive | 55 (17.6%) | 32 (26.0%) | ||
Pathological stage | 6.041 | 0.110 | ||
0 | 46 (14.7%) | 14 (11.4%) | ||
I | 162 (51.7%) | 54 (43.9%) | ||
II | 97 (31.0%) | 48 (39.0%) | ||
III | 8 (2.6%) | 7 (5.7%) | ||