Fig. 4

Comparison of dorsal vascular network of skin in each group after 10 days’ pretreatment. a General observation of vascular network. a, b and c were the results of normal saline pretreatment on day 4, day 7 and day 10; d, e and f were the results of GS-HuMSCs-CM pretreatment on day 4, day 7 and day 10; g, h and i were the results of HuMSCs pretreatment on day 4, day 7 and day 10. The red circle in the figure shows one of the main blood vessels in the back of mice. It can be observed that HuMSCs group and GS-HuMSCs-CM group had the most obvious increase in blood vessel branches on the 10 th day and more anastomosis with each other. b Anastomotic branches on day 10. (*P < 0.05; **P < 0.01)