Fig. 1

Expression profiles of OPN3 in normal tissues and LUAD. a OPN3 expression differences between LUAD and normal tissues in OPN3 from the TCGA database. b The expression intensity of OPN3 in LUAD tissues and normal tissues was accomplished through IHC using the Human Protein Atlas (HPA) database, utilizing the antibody CAB013682. c The correction between OPN3 expression and the pathological stages of LUAD using the GEPIA2 database. d Survival analysis of patients with high expression of OPN3 and low expression of OPN3 in LUAD on TIMER 2.0 website. Overall survival between the OPN3 high- and low-expression group in patients with LUAD by Kaplan–Meier analysis. e The basic endogenous expression of OPN3 in five distinct LUAD cell lines, *P < 0.05, **P < 0.01; means + SD