Fig. 3

Regional plot of candidate loci in the combined set. Figures show regional association plots of significant representative loci: a 2p23.3, b 19p13.11, and c 22q13.3. Purple shaded circles represent the most significant SNPs: rs1260326, rs58542925, and rs738409 located in 2p23.3, 19p13.11, and 22q13.3, respectively. Blue line indicates the recombination rate, while the filled color represents the linkage disequilibrium score based on r2 values estimated from the 1000 Genomes Nov 2014 ASN data