Prognostic role of minimum heart rate in elderly heart failure patients with hypertensive heart disease: an analysis of MIMIC-IV database

Table 3 MHR and outcomes in subgroups

Subgroup	30-day mortality		90-day mortality		1-year mortality
Subgroup	Hazard ratio (95% CI)	p value	Hazard ratio (95% CI)	p value	Hazard ratio (95% CI)	p value
Gender
Female (n = 1268)	1.422 (1.063–1.901)	0.018	1.362 (1.060–1.750)	0.016	1.274 (1.030–1.577)	0.026
Male (n = 1208)	1.108 (0.810–1.518)	0.521	1.003 (0.767–1.311)	0.984	1.059 (0.848–1.322)	0.614
AF
No (n = 937)	1.418 (0.977–2.058)	0.066	1.497 (1.091–2.056)	0.013	1.305 (0.997–1.708)	0.052
Yes (n = 1539)	1.266 (0.977–1.641)	0.075	1.123 (0.898–1.404)	0.309	1.14 (0.945–1.374)	0.171
COPD
No (n = 2203)	1.313 (1.052–1.638)	0.016	1.266 (1.047–1.530)	0.015	1.263 (1.075–1.484)	0.005
Yes (n = 273)	1.554 (0.683–3.539)	0.293	1.171 (0.589–2.328)	0.652	1.015 (0.608–1.693)	0.955
IHD
No (n = 883)	1.468 (1.064–2.024)	0.019	1.231 (0.926–1.635)	0.152	1.290 (1.014–1.642)	0.038
Yes (n = 1593)	1.222 (0.920–1.622)	0.166	1.222 (0.963–1.549)	0.098	1.130 (0.926–1.379)	0.228
Renal failure
No (n = 1048)	1.797 (1.220–2.647)	0.003	1.410 (1.010–1.968)	0.043	1.316 (1.003–1.726)	0.047
Yes (n = 1428)	1.212 (0.940–1.563)	0.137	1.195 (0.961–1.486)	0.108	1.188 (0.986–1.430)	0.07

Patients were grouped by sex, concomitant AF, COPD, IHD, or renal failure. The association between the two MHR groups and 30-day, 90-day, and 1-year all-cause mortalities was analyzed using Cox proportional hazards regression model after adjusting for variables. Hazard ratio and 95% confidence interval were calculated for comparison between the low MHR group and the high MHR group (as reference). P < 0.05 indicates statistical significance
AF atrial fibrillation, CI confidence interval, COPD chronic obstructive pulmonary disease, IHD ischemic heart disease, MHR minimum heart rate

ISSN: 2047-783X