Fig. 8

Quercetin treatment alleviates AS progression in ApoE^−/− mice. A H&E staining for detecting AS plaque formation in aorta tissues of ApoE^−/− mice receiving normal diet (ND), high-fat diet (HD), HD supplemented with quercetin (HD + Que), or HD supplemented with atorvastatin (HD + Ator) (n = 6 per group). Scale bar, 50 μm. B–D Measurement of B body weight, C average daily food intake, and D fasting blood glucose every two weeks. E–H Measurement of serum E TC, F TG, G HDL, and H LDL levels after treatment for 16 weeks. I–K Measurement of serum I IL-1β, J TNF-α, and K IL-6 levels after treatment for 16 weeks. ns, p > 0.05; *p < 0.05; **p < 0.01; ****p < 0.0001