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Table 3 Associations of MPV, NLR, PLR, SII index, SIRI and ALP with sarcopenia risk

From: Association of hematological parameters and inflammatory indices with sarcopenia in the United States and China: a cross-sectional study

 

Model 1

 

Model 2

 

Model 3

 
 

OR (95% CI)

P for trend

OR (95% CI)

P for trend

OR (95% CI)

P for trend

MPV

 

0.115

 

0.203

 

0.355

6.10–7.80

1.00

 

1.00

 

1.00

 

7.81–8.40

0.87 (0.55, 1.38)

 

0.85 (0.53, 1.36)

 

0.81 (0.50, 1.31)

 

8.41–8.90

0.95 (0.57, 1.58)

 

0.90 (0.53, 1.51)

 

0.83 (0.48, 1.42)

 

8.91–13.30

1.38 (0.89, 2.13)

 

1.31 (0.84, 2.06)

 

1.21 (0.76, 1.93)

 

NLR

 

0.079

 

0.227

 

0.512

0.28–1.36

1.00

 

1.00

 

1.00

 

1.37–1.82

0.99 (0.23, 1.74)

 

0.91 (0.48, 1.62)

 

0.90 (0.52, 1.55)

 

1.83–2.41

0.97 (0.52, 1.69)

 

0.90 (0.47, 1.60)

 

0.78 (0.45, 1.38)

 

2.42–17.43

1.54 (0.96, 2.46)

 

1.37 (0.84, 2.25)

 

0.85 (0.48, 1.48)

 

PLR

 

0.880

 

0.912

 

0.875

15.71–90.41

1.00

 

1.00

 

1.00

 

90.42–112.85

0.65 (0.40, 1.06)

 

0.65 (0.40, 1.06)

 

0.66 (0.40, 1.07)

 

112.86–139.41

0.75 (0.47, 1.20)

 

0.75 (0.47, 1.20)

 

0.73 (0.45, 1.19)

 

139.42–498.34

0.96 (0.61, 1.51)

 

0.96 (0.61, 1.51)

 

1.04 (0.65, 1.66)

 

SII index

 

 < 0.001

 

0.002

 

0.710

31.42–306.00

1.00

 

1.00

 

1.00

 

306.01–430.58

0.96 (0.35, 1.95)

 

0.92 (0.32, 1.82)

 

0.97 (0.48, 2.03)

 

430.59–608.12

0.86 (0.28, 1.82)

 

0.80 (0.27, 1.78)

 

0.81 (0.40, 1.55)

 

608.13–5848.31

2.73 (1.65, 4.49) ***

 

2.47 (1.47, 4.15) ***

 

1.29 (0.72, 2.30)

 

SIRI

 

0.003

 

0.038

 

0.517

0.00–0.62

1.00

 

1.00

 

1.00

 

0.63–0.92

0.96 (0.43, 2.02)

 

0.94 (0.54, 2.21)

 

0.93 (0.52, 1.68)

 

0.93–1.37

0.83 (0.38, 1.79)

 

0.88 (0.73, 1.84)

 

0.90 (0.47, 1.58)

 

1.38–17.69

2.23 (1.37, 3.64) **

 

1.90 (1.13, 3.20) *

 

1.49 (1.07, 2.53) *

 

ALP

 

 < 0.001

 

 < 0.001

 

 < 0.001

7.00–53.00

1.00

 

1.00

 

1.00

 

53.01–66.00

2.90 (1.36, 6.16) **

 

2.24 (1.04, 4.82) *

 

1.76 (0.77, 3.98)

 

66.01–85.00

2.94 (1.39, 6.24) **

 

2.60 (1.22, 5.56) *

 

2.23 (0.98, 5.04)

 

85.01–907.00

9.10 (4.50, 18.41) ***

 

5.90 (2.84, 12.28) ***

 

4.80 (2.18, 10.55) ***

 
  1. Model 1: age and sex. Model 2: model 1 variables plus race/ethnicity, education level, marital status, family poverty-income ratio, the complication of hypertension, and diabetes mellitus, smoker, and alcohol user; Model 3 was adjusted for model 2 variables plus mean energy intake, fast glucose, calcium, phosphorus, total cholesterol, triglyceride, high-density lipoprotein-cholesterol, blood urea nitrogen, serum uric acid, serum creatinine, and estimated glomerular filtration rate
  2. MPV, mean platelet volume; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; SII, systemic immune inflammatory index; SIRI, systemic inflammation response index; ALP, alkaline phosphatase
  3. *P < 0.05; **P < 0.01; ***P < 0.001; OR, odd ratio; CI, confidence interval