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Table 4 Survival analysis of gastric cancer patients without LVI using univariate and multivariate Cox regression analyses

From: Development of the G-Risk scoring system utilizing inflammatory and tumor biomarkers to improve prognostic accuracy in gastric cancer patients without lymphovascular invasion

Characteristics

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Age

1.02 (1.01–1.03)

0

1.01 (1–1.02)

0.0208

Sex

    

 Male

Reference

 

Reference

 

 Female

0.88 (0.7–1.11)

0.282

NA

NA

pTNM

    

 I

Reference

 

Reference

 

 II

3.57 (2.37–5.38)

0

1.74 (1.02–2.96)

0.0431

 III

11.35 (7.75–16.62)

0

4.88 (2.88–8.28)

0

 IV

39.11 (23.84–64.17)

0

16.41 (8.72–30.89)

0

Lauren

    

 Intestinal

Reference

 

Reference

 

 Diffuse

1.08 (0.87–1.35)

0.475

NA

NA

 Mixed

1.26 (0.95–1.67)

0.103

NA

NA

Borrmann

    

 0

Reference

 

Reference

 

 I

5.51 (2.56–11.87)

0

1.75 (0.73–4.24)

0.2122

 II

4.46 (2.55–7.82)

0

1.56 (0.76–3.19)

0.2247

 III

9.6 (5.79–15.91)

0

2.68 (1.35–5.32)

0.005

 IV

26.04 (14.95–45.34)

0

3.8 (1.78–8.1)

0.0004

Location

    

 Low

Reference

 

Reference

 

 Middle

1.36 (1.05–1.75)

0.018

1.02 (0.79–1.31)

0.9027

 Upper

1.98 (1.47–2.68)

0

1.83 (1.34–2.49)

0.0001

 Whole

6.68 (4.67–9.57)

0

2.56 (1.66–3.94)

0

 Tumor size

1.02 (1.02–1.02)

0

1 (1–1)

0.8357

G risk score

    

 Low risk

Reference

 

Reference

 

 High risk

2.66 (2.18–3.25)

0

1.64 (1.31–2.04)

0