Fig. 4

CBS exerts beneficial effects on gut microbiota and related metabolites in obesity-related hypertensive rats. a Concentration of SCFAs in the serum of each group (n = 4–6). b Concentration of TMAO and its precursors in the serum of each group (n = 4–6). c Heatmap of the Spearman correlation analysis of the top 50 microbes associated with SCFAs and TMAO. The Spearman rank correlation coefficient (r) ranged from − 0.6 (blue) to 0.6 (red). d Relative abundance of genera between groups. *P < 0.05, **P < 0.01, versus OH-Sham; #P < 0.05, ##P < 0.01, versus C-sham. A, B, D statistical comparison: Kruskal–Wallis test