Fig. 2

Effects of HFHFD on gut microbial diversity and composition. a, b α-Diversity Chao1 index and Shannon index (n = 8–14). c Principal coordinate analysis (PCoA) score plot based on unweighted UniFrac metrics. d Relative abundances of the top 20 dominant phyla. e Relative abundances of the top 20 dominant genera. f Heatmap of the relative abundance of the top 50 dominant genera for each sample. g Cladogram generated from LEfSe analysis