Fig. 1

CBS controls the body weight gain and lowers blood pressure in obesity-related hypertensive rats. a Schematic representation of the study design. SD rats were fed with an HFHFD, or ND and sacrificed at 13 weeks. Fecal contents were collected at 0, 4 and 12 weeks. The CBS was implanted at 5 weeks. b Representative images of rat body size. c Comparison of visceral fat mass among the 4 groups. d Body weight change in rats. e Systolic blood pressure. f Diastolic blood pressure. g Mean arterial pressure. C-sham group, n = 7; C-CBS group, n = 6; OH-sham group, n = 7; OH-CBS group, n = 7. Results are expressed as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 versus OH-Sham; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 versus C-sham. FC: Fecal Collection; CBS: Carotid Baroreceptor Stimulation; HFHFD: High-Fat, High-Fructose Diet; ND: Normal Diet