Table 2 Univariate Analyses Results after missing value removal

Age(year)

0.97

0.93–1.01

0.176

BMI (kg/m²)

0.92

0.77–1.10

0.374

Family history

 No

Ref

 Yes

2.06

0.81–5.62

0.141

Marital status

 Unmarried

Ref

 Married

0.43

0.02–3.48

0.469

Menopause

 Premenopausal

 Menopause

1.23

0.44–3.68

0.694

Side classification

 Left

Ref

 Right

2.30

0.99–5.49

0.055

 Both

NC

NC

0.990

Pathological type

 Invasive cancer

Ref

 DCIS

NC

NC

0.98

Grade

 1

NC

NC

NC

 2

Ref

 3

3.07

1.23–8.12

0.019*

 Others

6.00

0.89–119.01

0.112

ER

 Negative

Ref

 Positive

0.32

0.13–0.77

0.011*

PR

 Negative

 Positive

0.32

0.13–0.78

0.014*

HER2

 Negative

Ref

 Low or positive

0.36

0.15–0.84

0.019*

Molecular subtype

 Luminal A

Ref

 Luminal B

2.00

0.22–43.12

0.568

 Triple-negative

6.50

0.77–136.50

0.116

 HER- 2 overexpression

3.00

0.07–170.77

0.547

T stage

 Tis- 1

Ref

 2–4

1.52

0.63–3.68

0.349

N stage

 0

Ref

 1–3

0.81

0.35–1.85

0.611

M stage

 0

Ref

 1

1.37

0.38–5.57

0.636

Stage

 0–II

Ref

 III–IV

1.20

0.50–2.95

0.686

CEA (ng/ml)

0.90

0.73–1.08

0.271

CA- 125 (U/ml)

1.00

1.00–1.01

0.430

CA153 (U/ml)

1.01

0.99–1.04

0.484

Ki- 67

32.18

4.22–306.29

0.001**