Fig. 6

Overexpression of MIR210HG promotes the p53 signaling pathway and is related to autophagy and apoptosis. A–C Changes in P53 protein expression in ESCC cells after overexpression of MIR210HG detected by western blot. D–F Changes in the expression of apoptosis and autophagy-related proteins in different subgroups of ESCC cells were detected by western blot in Vector, OE-MIR210HG, Vector + PFT-α, and OE-MIR210HG + PFT-α, respectively, and PFT-α was an inhibitor of the transcriptional activity of P53 protein. Error bars indicate the mean ± standard deviation of three independent experiments, ns (non-significant), *p < 0.05, **p < 0.01, ***p < 0.001