Table 1 A summary of studies investigating curcumin’s effects on muscle injury, fatigue, and damage
From: Polyphenols and post-exercise muscle damage: a comprehensive review of literature
Year of publication | Administration | Model of study | Result(s) | References |
|---|---|---|---|---|
2023 | A single daily dose for 12 weeks | Human study | Decreasing muscle fatigue score and the muscle soreness score only in men | [92] |
2023 | 28 days intragastric administration of either curcumin (58 mg/kg) or caffeine (6 mg/kg) | Animal study | Increasing quadriceps coefficient, muscle glycogen (MG) content, and increase in the expression of Akt, AMPK, PI3K, and mTOR proteins and curcumin decreased AMP/ATP ratio and lactic acid and increased glycogen synthase and myonectin | [93] |
2022 | 50, 100, and 200 mg of curcumin for 4 weeks | Animal study | Increasing exercise capacity and decreasing blood urea nitrogen, blood ammonia, lactic acid, creatine kinase, and lactate dehydrogenase especially in C100 | [94] |
2015 | 180 μg/mL by oral gavage at 0, 12.3, 24.6, or 61.5 mL/kg/day for 4 weeks | Animal study | Increasing exercise duration, decreasing serum lactate and ammonia and CK and AST and ALT | [95] |
2007 | 10 mg, oral, for 3 days prior to run | Animal study | Increasing running performance through decreasing IL-6, IL-1β and TNF-α | [96] |