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Table 1 Clinical features and univariate associations with diarrhea in STBI patients

From: Risk factors for enteral nutrition-associated diarrhea in older patients with severe traumatic brain injury: a retrospective cohort study

Variables

Age < 65 (n = 168)

Age ≥ 65 (n = 124)

Diarrhea (n = 56)

No Diarrhea (n = 112)

p value

Diarrhea (n = 58)

No Diarrhea (n = 66)

p value

Age (years)

52.61 ± 9.86

49.90 ± 12.09

0.249

73.53 ± 7.87

73.18 ± 6.71

0.961

Sex (M/F)

45/11

82/30

0.310

46/12

43/23

0.081

GCS

  

0.742

  

0.021

3–5

24

51

 

34

25

 

6–8

32

61

 

24

41

 

APACHE II

17.57 ± 6.02

13.91 ± 4.38

0.000

20.45 ± 4.90

17.67 ± 3.63

0.002

Hypertension (%)

12(21.43%)

20(17.86%)

0.578

28(48.28%)

36(54.55%)

0.486

Diabetes (%)

4(7.14%)

6(5.36%)

0.645

10(17.24%)

8(12.12%)

0.419

BMI (Kg/m2)

23.76 ± 3.12

23.20 ± 2.96

0.259

23.02 ± 3.97

22.67 ± 3.03

0.571

Fasting time (days)

1.27 ± 0.82

1.08 ± 0.75

0.205

1.21 ± 0.95

1.29 ± 1.08

0.614

Daily nutrient solution (mL)

1239 ± 258

1186 ± 270

0.198

1267 ± 254

1274 ± 275

0.794

High fat energy (%)

45(80.36%)

80(71.43%)

0.211

53(91.38%)

47(71.21%)

0.005

Enteral nutrition duration (days)

13.89 ± 9.28

8.77 ± 4.09

0.000

14.59 ± 6.01

9.36 ± 5.55

0.000

Serum albumin (g/L)

34.04 ± 7.20

36.70 ± 6.17

0.009

36.31 ± 5.67

36.51 ± 6.47

0.857

Antibiotics DDDs

15.86 ± 8.17

9.25 ± 5.07

0.000

15.53 ± 8.28

9.11 ± 5.64

0.000

Use prokinetic drugs (%)

46(82.14%)

87(77.68%)

0.502

45(77.59%)

50(75.76%)

0.810

Tube feeding of potassium (%)

32(57.14%)

52(46.43%)

0.190

38(65.52%)

27(40.91%)

0.006

  1. Values are mean ± SD
  2. STBI Severe Traumatic Brain Injury, GCS Glasgow Coma Scale, APACHE II Acute Physiology and Chronic Health Evaluation II, BMI Body Mass Index, DDDs Total Defined Daily Dose of Antibiotics