Fig. 4
From: Inducing mononuclear cells of patients with CADASIL to construct a CSVD disease model
Identification of vascular organoids differentiated from iPSCs. Green: α-SMA + ; red: CD31 + ; white: PDGFR-β + ; blue: DAPI. A Immunofluorescence:Green (CD31 +), Red (PDGFR-β +) and Blue (DAPI). B Multiplex immunofluorescence:Green (α-SMA +), red (CD31 +), white (PDGFR-β +) and blue (DAPI). B1 The vascular organoid was stained with the vascular smooth muscle cell marker α-SMA, the endothelial cell marker CD31, and the pericyte marker PDGFR-β. B2 Vascular smooth muscle cell marker α-SMA and DAPI. B3 Vascular endothelial cell marker CD31 and DAPI. B4 Vascular pericyte marker PDGFR-β and DAPI.E: Merge of figure B2, B3 and B4