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Fig. 3 | European Journal of Medical Research

Fig. 3

From: Inducing mononuclear cells of patients with CADASIL to construct a CSVD disease model

Fig. 3

Generation of vascular organoids from iPSCs. A Status of revived iPSCs in the CADASIL and control groups. B D-3 displays the initial morphology of the successfully resuscitated iPSCs in the control group and CADASIL group under 4 × and 10 × magnification; D-2 depicts the digestion of iPSCs into single cells; D-1 and D0 show the aggregation processes of single cells; D3 shows induced vascular mesoderm; D5 shows the beginning of the formation of sprouting blood vessels; D8 shows the beginning of the appearance of an endothelial network; D11 shows the production of a highly branched mature vascular network; and D13–D20 show isolated and continuously cultured single vascular organoids

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European Journal of Medical Research

ISSN: 2047-783X

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