Fig. 1

Identification and functional enrichment of key Enz resistance-related DEGs from the GEO database A Volcano plots illustrating the DEGs in dataset GSE51872, with red dots representing upregulated genes and blue dots representing downregulated genes. B Volcano plots illustrating the DEGs in dataset GSE56829, with red dots representing upregulated genes and blue dots representing downregulated genes. C Volcano plots illustrating the DEGs in dataset GSE69249, with red dots representing upregulated genes and blue dots representing downregulated genes. D Heatmap depicting the DEGs across various samples in dataset GSE51872. E Heatmap depicting the DEGs across various samples in dataset GSE56829. F Heatmap illustrating DEGs across various samples in dataset GSE69249. G GO pathway enrichment analysis of DEGs in dataset GSE51872. (H) GO pathway enrichment analysis of DEGs in dataset GSE56829. I GO pathway enrichment analysis of DEGs in dataset GSE69249. J KEGG pathway enrichment analysis of DEGs in dataset GSE51872. K KEGG pathway enrichment analysis of DEGs in dataset GSE56829. L KEGG pathway enrichment analysis of DEGs in dataset GSE69249