Table 1 Baseline characteristics of the patients
Variable | Before PSM | After PSM | ||||
|---|---|---|---|---|---|---|
No-PD-1 (n = 122) | PD-1 (n = 77) | p | Non-PD-1 (n = 65) | PD-1 (n = 65) | p | |
Age, mean ± SD | 55.86 ± 12.11 | 54.75 ± 9.53 | 0.474 | 55.78 ± 12.57 | 55.48 ± 9.02 | 0.873 |
Sex, n (%) | Â | Â | 0.443 | Â | Â | 0.571 |
 Male | 103 (84.43) | 68 (88.31) |  | 59 (90.77) | 57 (87.69) |  |
 Female | 19 (15.57) | 9 (11.69) |  | 6 (9.23) | 8 (12.31) |  |
WBC, mean ± SD | 5.82 ± 2.53 | 5.60 ± 1.54 | 0.448 | 5.80 ± 1.95 | 5.59 ± 1.62 | 0.510 |
PLT, mean ± SD | 168.19 ± 73.38 | 179.32 ± 76.93 | 0.307 | 178.66 ± 73.26 | 175.40 ± 71.15 | 0.797 |
Hemoglobin, mean ± SD | 134.11 ± 19.04 | 139.19 ± 18.57 | 0.065 | 138.83 ± 14.01 | 138.15 ± 19.59 | 0.821 |
ALT, mean ± SD | 28.61 ± 19.09 | 31.52 ± 35.52 | 0.455 | 30.37 ± 20.77 | 26.83 ± 15.45 | 0.272 |
ast, mean ± sd | 33.55 ± 17.34 | 29.81 ± 12.52 | 0.102 | 31.66 ± 13.65 | 29.52 ± 12.48 | 0.353 |
ALBI grade, n (%) | Â | Â | 0.313 | Â | Â | 0.706 |
 Grade 1 | 22 (18.03) | 12 (15.58) |  | 9 (13.85) | 11 (16.92) |  |
 Grade 2 | 93 (76.23) | 56 (72.73) |  | 51 (78.46) | 47 (72.31) |  |
 Grade 3 | 7 (5.74) | 9 (11.69) |  | 5 (7.69) | 7 (10.77) |  |
AFP, n (%) | Â | Â | 0.721 | Â | Â | 0.848 |
 < 400 ng/ml | 81 (66.39) | 53 (68.83) |  | 45 (69.23) | 46 (70.77) |  |
 ≥ 400 ng/mL | 41 (33.61) | 24 (31.17) |  | 20 (30.77) | 19 (29.23) |  |
DCP, n (%) | Â | Â | 0.815 | Â | Â | 0.553 |
 < 40 mAU/mL | 33 (27.05) | 22 (28.57) |  | 16 (24.62) | 19 (29.23) |  |
 ≥ 400 mAU/mL | 89 (72.95) | 55 (71.43) |  | 49 (75.38) | 46 (70.77) |  |
Viral infection, n (%) | Â | Â | 0.707 | Â | Â | 0.456 |
 HBV | 104 (85.25) | 68 (88.31) |  | 56 (86.15) | 57 (87.69) |  |
 HCV | 1 (0.82) | 1 (1.30) |  |  |  |  |
 No | 17 (13.93) | 8 (10.39) |  | 9 (13.85) | 8 (12.31) |  |
Cirrhosis, n (%) | Â | Â | 0.081 | Â | Â | 0.861 |
 No | 48 (39.34) | 40 (51.95) |  | 31 (47.69) | 32 (49.23) |  |
 Yes | 74 (60.66) | 37 (48.05) |  | 34 (52.31) | 33 (50.77) |  |
BCLC stage | Â | Â | 0.166 | Â | Â | 0.979 |
 0–A | 87 (71.31) | 45 (58.44) |  | 40 (61.54) | 41 (63.08) |  |
 B | 11 (9.02) | 9 (11.69) |  | 8 (12.31) | 8 (12.31) |  |
 C | 24 (19.67) | 23 (29.87) |  | 17 (26.15) | 16 (24.62) |  |
Types of hepatectomy, n (%) | Â | Â | 0.360 | Â | Â | 0.860 |
 Anatomical | 60 (49.18) | 43 (55.84) |  | 34 (52.31) | 35 (53.85) |  |
 Non-anatomical | 62 (50.82) | 34 (44.16) |  | 31 (47.69) | 30 (46.15) |  |
Tumor size, n (%) | Â | Â | 0.022 | Â | Â | 0.714 |
 ≤ 5 cm | 58 (47.54) | 24 (31.17) |  | 22 (33.85) | 24 (36.92) |  |
 > 5 cm | 64 (52.46) | 53 (68.83) |  | 43 (66.15) | 41 (63.08) |  |
Tumor number, n (%) | Â | Â | 0.993 | Â | Â | 0.517 |
 Single | 95 (77.87) | 60 (77.92) |  | 53 (81.54) | 50 (76.92) |  |
 Multiple | 27 (22.13) | 17 (22.08) |  | 12 (18.46) | 15 (23.08) |  |
Edmondson–Steiner grade, n (%) |  |  | 0.370 |  |  | 0.860 |
 III/IV | 65 (53.28) | 36 (46.75) |  | 30 (46.15) | 31 (47.69) |  |
 I/II | 57 (46.72) | 41 (53.25) |  | 35 (53.85) | 34 (52.31) |  |
MVI, n (%) | Â | Â | 0.055 | Â | Â | 1.000 |
 No | 58 (47.54) | 26 (33.77) |  | 25 (38.46) | 25 (38.46) |  |
 Yes | 64 (52.46) | 51 (66.23) |  | 40 (61.54) | 40 (61.54) |  |
Macrovascular invasion, n (%) | Â | Â | 0.123 | Â | Â | 0.833 |
 No | 100 (81.97) | 56 (72.73) |  | 51 (78.46) | 50 (76.92) |  |
 Yes | 22 (18.03) | 21 (27.27) |  | 14 (21.54) | 15 (23.08) |  |
Capsular invasion, n (%) | Â | Â | 0.815 | Â | Â | 0.545 |
 No | 89 (72.95) | 55 (71.43) |  | 50 (76.92) | 47 (72.31) |  |
 Yes | 33 (27.05) | 22 (28.57) |  | 15 (23.08) | 18 (27.69) |  |
Satellite nodules, n (%) | Â | Â | 0.457 | Â | Â | 0.708 |
 No | 81 (66.39) | 55 (71.43) |  | 43 (66.15) | 45 (69.23) |  |
 Yes | 41 (33.61) | 22 (28.57) |  | 22 (33.85) | 20 (30.77) |  |
TACE, n (%) | Â | Â | 0.169 | Â | Â | 0.856 |
 No | 83 (68.03) | 45 (58.44) |  | 41 (63.08) | 40 (61.54) |  |
 Yes | 39 (31.97) | 32 (41.56) |  | 24 (36.92) | 25 (38.46) |  |