Variables | Study (n = 30) | Control (n = 30) | X2/t | P value |
---|---|---|---|---|
Age (years) mean ± SD | 40.43 ± 8.39 | 39.53 ± 8.08 | 0.423 | 0.674 |
Age group n (%) | ||||
18 > 30 years n (%) | 3 (10.0) | 4 (13.3) | 0.363 | 0.948 |
30 > 40 years n (%) | 15 (50.0) | 16 (53.3) | ||
40 > 50 years n (%) | 7 (23.3) | 6 (20.0) | ||
50–65 years n (%) | 5 (16.7) | 4 (13.3) | ||
Gender | ||||
Male n (%) | 17 (56.7) | 21 (70.0) | 1.148 | 0.284 |
Female n (%) | 13 (43.3) | 9 (30.0) | ||
Predisposing factors for perforated peptic ulcer | ||||
History of peptic ulcer treatment n (%) | 7 (23.3) | 11 (36.7) | 1.270 | 0.260 |
Smoking n (%) | 7 (23.3) | 14 (46.7) | 3.590 | 0.058 |
Stress n (%) | 16 (53.3) | 14 (46.7) | 0.267 | 0.606 |
NSAIDs use n (%) | 15 (50.0) | 20 (66.7) | 1.714 | 0.190 |
Spicy food n (%) | 4 (13.3) | 9 (30) | 2.455 | 0.117 |
Current health history | ||||
Co-morbid n (%) | 4 (13.3) | 7 (23.3) | 1.002 | 0.317 |
Shock on admission n (%) | 25 (83.3) | 27 (90.0) | 0.577 | 0.448 |
Delayed surgery > 6 h. of admission n (%) | 16 (53.3) | 18 (60.0) | 0.271 | 0.602 |
Preoperative investigations | ||||
Metabolic acidosis n (%) | 10 (33.3%) | 14 (46.7%) | 1.111 | 0.292 |
Hemoglobin < 6.0 mmol/l n (%) | 11 (36.7%) | 10 (33.3%) | 0.073 | 0.787 |
Creatinine > 110/130 µmol/l n (%) | 6 (20%) | 8 (26.7%) | 0.373 | 0.542 |
Albumin < 550 µmol/l n (%) | 9 (30%) | 10 (33.3%) | 0.077 | 0.781 |
Site of perforation | ||||
Stomach n (%) | 3 (10.0) | 2 (6.7) | 0.218 | 0.640 |
Duodenum n (%) | 27 (90.0) | 28 (93.3) | ||
Size of ulcer | ||||
< 5 mm n (%) | 25 (83.3) | 24 (80.0) | 0.111 | 0.739 |
≥ 5 mm n (%) | 5 (16.7) | 6 (20.0) | ||
Duration of symptoms | ||||
≥ 24 h n (%) | 18 (60.0) | 20 (66.7) | 4.286 | 0.788 |
< 24 h n (%) | 12 (40.0) | 10 (33.3) | ||
Duration of operation | ||||
< 2 s n (%) | 19 (63.3) | 19 (63.3) | 1.048 | 0.592 |
2–4 h n (%) | 10 (33.3) | 11 (36.7) | ||
> 4 h n (%) | 1 (3.3) | 0 (0.0) |