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Table 4 The starting dose of PCSK9 inhibitors

From: Lower body mass index is associated with the achievement of target LDL in patients using PCSK9 inhibitors in Taiwan

Alirocumab

LDL target non-achiever N = 73

LDL target achiever N = 82

P value

75 mg Q2W

62 (84.9)

140 mg Q2W

69 (84.2)

1.000

75 mg Q3W to Q4W

9 (12.3)

140 mg Q3W to Q4W

13 (15.9)

0.691

150 mg Q4W

0 (0.0)

420 mg Q4W

0 (0.0)

0.000

*Others

2 (2.7)

Others

0 (0.0)

0.000

Evolocumab

LDL target non-achiever N = 18

LDL target achiever N = 38

P value

75 mg Q2W

11 (61.1)

140 mg Q2W

29 (76.3)

0.390

75 mg Q3W to Q4W

3 (16.7)

140 mg Q3W to Q4W

2 (5.3)

0.314

140 mg Q4W

3 (3.3)

420 mg Q4W

2 (5.3)

0.314

*Others

1 (5.6)

Others

5 (13.2)

0.652

  1. Q2W: every 2 weeks; Q3W: every 3 weeks; Q4W: every 4 weeks
  2. *Others indicated irregular use without specific intervals