Table 1 Preoperative assessment of HCC in the presence of MVI multi-omics studies
From: Advances in multi-omics studies of microvascular invasion in hepatocellular carcinoma
Serial no. | Title | Author | Date of publication | Journal | Page | Number | Method | Type |
|---|---|---|---|---|---|---|---|---|
1 | Using preoperative radiomics to predict the microvascular invasion of hepatocellular carcinoma based on Gd-EOB-DTPA enhanced MRI [7] | Xin-Yu Lu | 2022 Sep | Randomized Controlled Trial | 1–13 | 165 | D value | Radiomics |
2 | A radiomics nomogram for preoperative prediction of microvascular invasion risk in hepatitis B virus-related hepatocellular carcinoma [12] | Jie Peng | 2018 May–Jun | Diagn Interv Radiol | 121–127 | 304 | Tumor margins not smooth, halo sign, presence of internal arteries | Radiomics |
3 | S100P as a novel biomarker of microvascular invasion and portal vein tumor thrombus in hepatocellular carcinoma [30] | Lu-Nan Qi | 2021 Feb | Hepatol Int | 114–126 | 826 | S100P overexpression | Genomics |
4 | A predictive and prognostic model for hepatocellular carcinoma with microvascular invasion based TCGA database genomics [32] | Jin Wang | 2021 Dec | BMC Cancer | 1–11 | 260 | HOXD9, HOXD10overexpression | Genomics |
5 | The effect of PPP2CA expression on the prognosis of patients with hepatocellular carcinoma and its molecular biological characteristics [33] | Jingchang Liang | 2021 Dec | J Gastrointest Oncol | 3008–3021 | 128 | PPP2CAoverexpression | Genomics |
6 | Gene expression signature as a surrogate marker of microvascular invasion on routine hepatocellular carcinoma biopsies [34] | Aurélie Beaufrère | 2022 Feb | J Hepatol | 343–352 | 178 | ROS1, UGT2B7, FAS, ANGPTL7, GMNN, MKI67 gene mutation | Genomics |
7 | Quantitative proteomic analysis identified paraoxonase 1 as a novel serum biomarker for microvascular invasion in hepatocellular carcinoma [37] | Cheng Huang | 2013 Apr | J Proteome Res | 1838–46 | 90 | Serum PON1 protein concentration | Proteomics |
8 | ORM 1 as a biomarker of increased vascular invasion and decreased sorafenib sensitivity in hepatocellular carcinoma [38] | Jiangning Gu | 2022 Oct | Bosn J Basic Med Sci | 949–958 | 35 | Increased ORM1 expression levels | Proteomics |
9 | SELDI-TOF MS Analysis of Hepatocellular Carcinoma in an Australian Cohort [39] | Steven M Schlichtemeier | 2019 Jun | J Surg Res | 127–136 | 30 | m/z9961low | Proteomics |
10 | Contribution of virtual biopsy to the screening of microvascular invasion in hepatocellular carcinoma: A pilot study [40] | Nicolas Poté | 2018 Apr | Liver Int | 687–694 | 106 | Increased H4K20me2, H4K16acexpression levels | Proteomics |
11 | Serum metabolites may be useful markers to assess vascular invasion and identify normal alpha-fetoprotein in hepatocellular carcinoma undergoing liver resection: a pilot study [44] | Chao-Wei Lee | 2020 Jun | World J Surg Oncol | 1–12 | 57 | Carboxylic acid ester | Proteomics |