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Table 4 Prediction of HFNC success based on cut-offs

From: Comparison of ROX index with modified indices incorporating heart rate, flow rate, and PaO2/FiO2 ratio for early prediction of outcomes among patients initiated on post-extubation high-flow nasal cannula therapy

 

Sensitivity (%)

Specificity (%)

NPV (%)

PPV (%)

LR + 

LR-

Youden index

2 h ROX > 12.40

65.7

85.7

34.3

95.7

4.59

0.40

0.514

2 h ROX-HR > 12.13

71.6

85.7

38.7

96.0

5.01

0.33

0.573

2 h ROX-HR Flow > 12.25

77.6

85.7

44.4

96.3

5.43

0.26

0.633

Post-HFNC POX-HR flow > 10.45#

74.2

76.9

38.5

93.9

3.21

0.34

0.511

  1. # 1.42 h (IQR 1.03–3.08) post-HFNC initiation
  2. NPV negative predictive value, PPV positive predictive value, LR likelihood ratio