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Table 1 Results of univariate logistic regression analysis examining the relationship between variables and the occurrence of AKI in patients with MSAP and SAP within the training cohort

From: Establishment and validation of a prediction model for acute kidney injury in moderate severe and severe acute pancreatitis patients

Variables

p value

Odd ratio

95% Confidence interval

Male

0.131

1.31

0.92–1.87

Age, (years)

0.045

1.01

1.00–1.02

Hypertension

0.012

1.55

1.10–2.19

Diabetes

0.389

1.17

0.82–1.69

Circulatory disease

0.867

0.94

0.47–1.91

CKD

0.204

1.74

0.74–4.10

Cancer history

0.452

0.68

0.24–1.88

Smoking

0.190

1.25

0.90–1.74

Drinking

0.280

1.20

0.86–1.69

AP etiology

   

 Biliary AP

  

Reference

 Hyperlipidemic AP

0.484

0.87

0.59–1.29

 Alcoholic AP

0.921

0.97

0.48–1.94

 Other

0.094

0.53

0.25–1.12

 Mixed AP

0.067

1.59

0.97–2.59

BMI, (kg/m2)

0.411

1.02

0.98–1.05

Vital sign

   

 RR, (bpm)

 < 0.001

1.05

1.02–1.07

 T, (℃)

0.777

1.03

0.82–1.30

 Shock Index

 < 0.001

17.63

7.27–42.79

Laboratory result

   

WBC, (109/L)

   

 [4, 12]

  

Reference

 < 4 or > 12

0.054

0.72

0.52–1.01

NLR

0.277

1

1.00–1.01

PLR

0.155

1

1.00–1.00

SII

0.264

1

1.00–1.00

Hb, (g/L)

   

 [120, 160]

  

Reference

 < 120

0.158

1.35

0.89–2.05

 > 160

0.04

2.12

1.27–3.53

HCT

   

 [0.3, 0.5]

  

Reference

 < 0.3

0.005

2.19

1.26–3.82

 > 0.5

 < 0.001

5.38

2.18–13.32

PLT, (109/L)

   

 [150, 300]

  

Reference

 < 150

 < 0.001

2.05

1.45–2.88

 > 300

0.449

1.34

0.63–2.85

CRP, (mg/L)

 < 0.001

1.004

1.002–1.005

Glucose, (mmol/L)

 < 0.001

1.08

1.04–1.12

Lactate, (mmol/L)

0.002

1.24

1.08–1.42

PCT, (ng/mL)

 < 0.001

1.11

1.07–1.14

ALT, (IU/L)

0.16

1.001

1.000–1.003

AST, (IU/L)

 < 0.001

1.003

1.001–1.005

ALP, (IU/L)

0.62

0.996

0.996–1.003

γ-GT, (IU/L)

0.989

1

0.999–1.001

Alb, (g/L)

0.002

0.95

0.92–0.98

Prealbmin, (mg/L)

0.143

0.998

0.995–1.001

TB, (μmol/L)

0.027

1.01

1.001–1.013

DB, (μmol/L)

0.001

1.02

1.01–1.03

SCr, (μmol/L)

 < 0.001

1.36

1.27–1.44

BUN, (mmol/L)

 < 0.001

1.005

1.004–1.006

Na+, (mmol/L)

   

 [135, 145]

  

Reference

 < 135

0.021

1.61

1.07–2.42

 > 145

 < 0.001

3.3

1.85–5.88

K+, (mmol/L)

   

 [3.5, 5.5]

  

Reference

 < 3.5

0.002

0.49

0.31–0.76

 > 5.5

0.003

5.6

1.78–17.62

Cl−, (mmol/L)

   

 [96, 108]

  

Reference

 < 96

0.279

1.66

0.66–4.14

 > 108

 < 0.001

2.33

1.56–3.48

P < 0.8 mmol/L

0.046

0.71

0.51–0.99

Ca2+, (mmol/L)

 < 0.001

0.12

0.07–0.23

CK-MB > 4 ng/mL

 < 0.001

5.78

3.75–8.90

MYO > 70 ng/mL

 < 0.001

7.13

4.84–10.51

TnI > 30 pg/mL

 < 0.001

2.58

1.82–3.65

pH

   

 [7.35, 7.45]

  

Reference

 < 7.35

 < 0.001

2.27

1.58–3.28

 > 7.45

0.255

0.61

0.26–1.43

PaO2, (Kpa)

0.472

1.01

0.98–1.05

PaCO2, (Kpa)

0.017

0.8

0.67–0.96

BE, (mmol/L)

   

 [− 3, 3]

  

Reference

 > 3

0.78

0.8

0.17–3.81

 < − 3

 < 0.001

2.54

1.77–3.63

TG, (mmol/L)

0.009

1.02

1.01–1.03

TC, (mmol/L)

0.674

1.01

0.97–1.05

APTT, (s)

   

 [35, 45]

  

Reference

 < 35

0.06

0.69

0.47–1.02

 > 45

 < 0.001

4.07

1.92–8.65

PT, (s)

   

 [10, 16]

  

Reference

 > 16

 < 0.001

4.53

2.70–7.62

TT, (s)

   

 [14, 21]

  

Reference

 < 14

0.43

1.32

0.67–2.60

 > 21

 < 0.001

2.71

1.64–4.47

Fg, (g/L)

   

 [1.8, 3.5]

  

Reference

 > 3.5

0.54

1.15

0.74–1.78

 < 1.8

0.25

2.31

0.55–9.78

FDP-1, (mg/L)

 < 0.001

1.02

1.01–1.04

d-Dimer, (mg/L)

 < 0.001

1.09

1.05–1.12