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Table 5 Multivariate logistic regression analysis results of the CLBR per oocyte retrieval cycle in different groups

From: Effect of letrozole cotreatment in progestin-primed ovarian stimulation on IVF/ICSI outcomes in POSEIDON group 3 and 4 poor responders: a retrospective cohort study

Parameters

POSEIDON Group 3

POSEIDON Group 4

aOR (95% CI)

P value

aOR (95% CI)

P value

PPOS

1.00 (Reference)

 

1.00 (Reference)

 

PPOS + LE

1.34 (0.64–2.83)

0.441

0.95 (0.43–2.09)

0.892

Age (year)

1.04 (0.89–1.23)

0.607

0.79 (0.70–0.91)

< 0.001*

BMI (kg/m2)

1.000 (0.89–1.12)

0.960

0.92 (0.81–1.04)

0.188

AMH (ng/ml)

0.97 (0.66–1.44)

0.893

0.87 (0.40–1.88)

0.722

AFC

0.89 (0.73–1.09)

0.261

0.91 (0.73–1.14)

0.406

Infertility duration (year)

0.83 (0.71–0.98)

0.026*

0.92 (0.81–1.05)

0.241

Fertilization methods

IVF

1.00 (Reference)

 

1.00 (Reference)

 

ICSI

0.79 (0.31–2.06)

0.633

1.20 (0.48–3.02)

0.694

No. of oocytes retrieved

0.71 (0.45–1.11)

0.130

0.64 (0.37–1.11)

0.114

No. of MII oocytes

1.30 (0.75–2.26)

0.346

1.38 (0.67–2.86)

0.384

No. of 2PN embryos

1.25 (0.79–1.98)

0.332

1.08 (0.66–1.78)

0.747

No. of available embryos

2.28 (1.37–3.78)

0.001*

2.51 (1.48–4.23)

< 0.001*

  1. Adjustments were made for age, BMI, duration of infertility, AMH, AFC and fertilization method, the number of oocytes retrieved, number of MII oocytes, number of 2PN embryos, and number of available embryos
  2. *P < 0.05
  3. BMI body mass index, AFC antral follicle count, AMH anti-Müllerian hormone, IVF in vitro fertilization, ICSI intracytoplasmic sperm injection, CLBR cumulative live birth rate, OR odds ratio, CI confidence interval, 2PN two pronuclei