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Table 3 Characteristics of embryo transfer and pregnancy outcomes in different groups

From: Effect of letrozole cotreatment in progestin-primed ovarian stimulation on IVF/ICSI outcomes in POSEIDON group 3 and 4 poor responders: a retrospective cohort study

Variables

POSEIDON Group 3

P value

POSEIDON Group 4

P value

PPOS group

n = 78

PPOS + LE group

n = 111

PPOS group

n = 154

PPOS + LE group

n = 214

Transfer outcomes

No. of patients

61

97

 

112

175

 

No. of total FET cycles

86

123

 

156

227

 

No. of total embryos transferred

103

138

 

192

270

 

Average of embryos transferred per cycle

1.2 ± 0.4

1.1 ± 0.3

0.136

1.2 ± 0.4

1.2 ± 0.4

0.327

No. of embryos transferred per cycle

  

0.135

  

0.326

1

69/86

(80.23)

108/123

(87.80)

 

120/156

(76.92)

184/227

(81.06)

 

2

17/86

(19.77)

15/123

(12.20)

 

36/156

(23.08)

43/227

(18.94)

 

Stage of embryo transferred, n (%)

  

0.649

  

0.281

Cleavage embryo

65/103

(63.11)

91/138

(65.94)

 

167/192

(86.98)

225/270

(83.33)

 

Blastocyst

38/103

(36.89)

47/138

(34.06)

 

25/192

(13.02)

45/270

(16.67)

 

Endometrial thickness (mm)

9.0

(8.3, 9.7)

9.1

(8.5, 10.1)

0.207

9.0

(8.2, 9.8)

9.2

(8.4, 10.0)

0.128

Endometrial preparation, n (%)

  

0.526

  

0.193

HRT cycles

67/86

(77.91)

104/123

(84.55)

 

111/156

(71.15)

176/227

(77.53)

 

Nature cycles

6/86

(6.98)

4/123

(3.25)

 

11/156

(7.05)

20/227

(8.81)

 

Ovulation induction cycles

1/86

(1.16)

1/123

(0.81)

 

3/156

(1.92)

2/227

(0.88)

 

Down-regulation + HRT cycles

12/86

(13.95)

14/123

(11.38)

 

31/156

(19.87)

29/227

(12.78)

 

Pregnancy outcomes, n (%)

      

Biochemical pregnancy rate

44/86

(51.16)

63/123

(51.22)

0.994

35/156

(22.44)

53/227

(23.35)

0.835

Clinical pregnancy rate

31/86

(36.05)

54/123

(43.90)

0.255

29/156

(11.33)

37/227

(16.30)

0.560

Ongoing pregnancy rate

24/86

(27.91)

44/123

(35.77)

0.232

17/156

(10.90)

25/227

(11.01)

0.972

Miscarriage rate

7/31

(22.58)

12/54

(22.22)

0.970

13/29

(44.83)

15/37

(40.54)

0.727

Live birth rate

24/86

(27.91)

42/123

(34.15)

0.340

16/156

(10.26)

22/227

(9.69)

0.856

Cumulative clinical pregnancy rate

31/78

(39.74)

54/111

(48.65)

0.226

29/154

(18.83)

37/214

(17.29)

0.704

Cumulative live birth rate

24/78

(30.77)

42/111

(37.84)

0.316

16/154

(10.39)

22/214

(10.28)

0.973

  1. Data were presented as mean ± SD, median (25th percent, 75th percent) and n (%)
  2. FET: Frozen embryo transfer; HRT: Hormone replacement therapy
  3. *P < 0.05