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Table 2 Baseline characteristics of the study population according to the AIP quartiles

From: Comparisons of three novel markers for insulin resistance to predict incident cardiovascular disease: a Korean cohort study from three different regions

Characteristics

Overall (n = 28,437)

Q1 (n = 7100)

Q2 (n = 7069)

Q3 (n = 7167)

Q4 (n = 7101)

P valuea

Post hocb

AIP

− 0.01 ± 0.30

 ≤ − 0.23

− 0.22–− 0.03

− 0.02–0.19

 ≥ 0.20

  

Age (years)

47.6 ± 10.7

44.6 ± 10.8

47.7 ± 10.8

49.0 ± 10.5

49.1 ± 10.1

 < 0.001

a,b,c,d,e

Body mass index (kg/m2)

22.6 ± 3.9

21.3 ± 3.0

22.4 ± 3.5

23.2 ± 4.0

23.4 ± 4.4

 < 0.001

a,b,c,d,e,f

Male sex (%)

51.1

28.6

45.9

59.3

70.4

 < 0.001

–

Current smoker (%)

22.8

15.1

20.6

26.4

28.8

 < 0.001

–

Alcohol drinking (%)

34.5

29.2

32.0

35.7

41.0

 < 0.001

–

Systolic blood pressure (mmHg)

121.9 ± 16.8

116.1 ± 15.5

120.7 ± 16.4

124.1 ± 16.6

126.9 ± 16.7

 < 0.001

a,b,c,d,e,f

Diastolic blood pressure (mmHg)

77.4 ± 10.9

72.9 ± 10.1

76.4 ± 10.5

78.9 ± 10.7

81.3 ± 10.6

 < 0.001

a,b,c,d,e,f

Mean arterial pressure (mmHg)

92.2 ± 12.3

87.3 ± 11.4

91.2 ± 11.9

94.0 ± 12.0

96.5 ± 11.9

 < 0.001

a,b,c,d,e,f

Fasting plasma glucose (mg/dl)

94.0 ± 20.5

88.7 ± 13.8

92.2 ± 17.3

95.6 ± 21.4

99.4 ± 25.9

 < 0.001

a,b,c,d,e,f

Total cholesterol (mg/dl)

192.1 ± 35.2

182.2 ± 31.5

187.8 ± 33.2

196.0 ± 35.2

202.2 ± 37.4

 < 0.001

a,b,c,d,e,f

Triglyceride (mg/dl)

133.8 ± 97.0

63.2 ± 14.3

93.1 ± 17.9

131.7 ± 26.2

247.0 ± 130.4

 < 0.001

a,b,c,d,e,f

HDL-cholesterol (mg/dl)

52.1 ± 12.6

64.7 ± 11.6

54.3 ± 9.3

48.0 ± 8.0

41.3 ± 7.1

 < 0.001

a,b,c,d,e,f

C-reactive protein (mg/L)

1.1 ± 3.4

0.8 ± 2.6

1.0 ± 3.2

1.2 ± 4.5

1.2 ± 2.9

 < 0.001

a,b,c,d,e

eGFR (mL/min/1.73 m2)

86.8 ± 17.4

88.0 ± 16.9

87.2 ± 17.5

86.3 ± 17.2

85.8 ± 17.7

 < 0.001

a,b,c,d,e

Hypertension medication (%)

11.0

5.4

9.1

12.8

16.8

 < 0.001

 

Diabetes medication (%)

11.4

4.6

9.3

13.5

18.2

 < 0.001

–

Dyslipidemia medication (%)

2.3

1.2

2.1

2.5

3.3

 < 0.001

–

  1. aP values were calculated using 1-way ANOVA or chi-squared test
  2. bPost hoc analysis with the Bonferroni method: a, Q1 vs. Q2; b, Q1 vs. Q3; c, Q1 vs. Q4; d, Q2 vs. Q3; e, Q2 vs. Q4; and f, Q3 vs. Q4
  3. AIP: Atherogenic index of plasma; HDL-C: High-density lipoprotein cholesterol; eGFR: estimated glomerular filtration rate
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European Journal of Medical Research

ISSN: 2047-783X

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