Table 1 Baseline characteristics of the study population according to the TyG index quartiles
Characteristics | Overall (n = 28,437) | Q1 (n = 7114) | Q2 (n = 7177) | Q3 (n = 7000) | Q4 (n = 7146) | P-valuea | Post hocb |
|---|---|---|---|---|---|---|---|
TyG index | 8.57 ± 0.61 |  ≤ 8.13 | 8.14–8.52 | 8.53–8.94 |  ≥ 8.95 |  |  |
Age (years) | 47.6 ± 10.7 | 44.2 ± 10.6 | 47.4 ± 10.8 | 49.2 ± 10.5 | 49.6 ± 10.0 |  < 0.001 | a,b,c,d,e |
Body mass index (kg/m2) | 22.6 ± 3.9 | 21.3 ± 3.1 | 22.3 ± 3.5 | 23.1 ± 4.0 | 23.6 ± 4.4 |  < 0.001 | a,b,c,d,e,f |
Male sex (%) | 51.1 | 30.3 | 45.8 | 57.8 | 70.6 |  < 0.001 | – |
Current smoker (%) | 22.8 | 14.7 | 21.1 | 25.3 | 29.9 |  < 0.001 | – |
Alcohol drinking (%) | 34.5 | 27.8 | 32.1 | 35.2 | 42.9 |  < 0.001 | – |
Systolic blood pressure (mmHg) | 121.9 ± 16.8 | 115.0 ± 14.9 | 120.2 ± 16.3 | 124.4 ± 16.5 | 128.3 ± 16.6 |  < 0.001 | a,b,c,d,e,f |
Diastolic blood pressure (mmHg) | 77.4 ± 10.9 | 72.3 ± 9.7 | 76.1 ± 10.4 | 79.2 ± 10.5 | 81.9 ± 10.5 |  < 0.001 | a,b,c,d,e,f |
Mean arterial pressure (mmHg) | 92.2 ± 12.3 | 86.6 ± 10.9 | 90.8 ± 11.8 | 94.2 ± 11.8 | 97.4 ± 11.8 |  < 0.001 | a,b,c,d,e,f |
Fasting plasma glucose (mg/dl) | 94.0 ± 20.5 | 85.6 ± 8.2 | 90.1 ± 9.9 | 93.5 ± 13.0 | 106.6 ± 33.2 |  < 0.001 | a,b,c,d,e,f |
Total cholesterol (mg/dl) | 192.1 ± 35.2 | 176.5 ± 30.4 | 187.6 ± 31.5 | 197.4 ± 33.7 | 206.8 ± 37.6 |  < 0.001 | a,b,c,d,e,f |
Triglyceride (mg/dl) | 133.8 ± 97.0 | 61.5 ± 11.8 | 93.1 ± 13.4 | 133.3 ± 21.7 | 247.1 ± 130.2 |  < 0.001 | a,b,c,d,e,f |
HDL-cholesterol (mg/dl) | 52.1 ± 12.6 | 60.0 ± 12.5 | 54.4 ± 11.9 | 49.4 ± 10.7 | 44.4 ± 9.3 |  < 0.001 | a,b,c,d,e,f |
C-reactive protein (mg/L) | 1.1 ± 3.4 | 0.9 ± 3.0 | 1.0 ± 3.5 | 1.2 ± 3.8 | 1.2 ± 3.2 |  < 0.001 | b,c,e |
eGFR (mL/min/1.73 m2) | 86.8 ± 17.4 | 88.5 ± 17.2 | 87.3 ± 17.4 | 86.0 ± 17.1 | 85.5 ± 17.5 |  < 0.001 | a,b,c,d,e |
Hypertension medication (%) | 11.0 | 4.3 | 7.4 | 11.8 | 20.6 |  < 0.001 | – |
Diabetes medication (%) | 11.4 | 3.9 | 8.2 | 12.8 | 20.7 |  < 0.001 | – |
Dyslipidemia medication (%) | 2.3 | 0.9 | 1.6 | 2.6 | 4.1 |  < 0.001 | – |