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Fig. 6 | European Journal of Medical Research

Fig. 6

From: Long non-coding RNA H19 promotes cervical cancer development via targeting the microRNA-140/ALDH1A1 axis

Fig. 6

LncRNA H19 targeted miR-140/ALDH1A1 axis in cervical cancer cells. A The binding sites of ALDH1A1 and miR-140 through mirwalk database. B Dual-luciferase reporter assay was performed to demonstrate the targeting interactions between ALDH1A1 and miR-140. ** P < 0.01 compared to the mimic NC group. C The mRNA expression levels of ALDH1A1 were examined in cervical cancer cells (Hela, Ca-Ski, and C33a) and normal cervical epithelial H8 cells. ** P < 0.01 compared to H8 cells, ## P < 0.01 compared to Ca-Ski cells, and $$ P < 0.01 compared to C33a cells. D The mRNA expression levels of ALDH1A1 were analyzed. E The protein expression level of ALDH1A1 was examined in cervical cancer cells (Hela, Ca-Ski, and C33a) and normal cervical epithelial H8 cells. ** P < 0.01 compared to H8 cells. F Western blotting was employed to explore the protein expression levels of ALDH1A1. ** P < 0.01 compared to the vector group, ## P < 0.01 compared to the sh-H19 + inhibitor NC group

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European Journal of Medical Research

ISSN: 2047-783X

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