Fig. 2

The malignant biological properties of cervical cancer cells were inhibited upon suppression of lncRNA H19. Hela cells were transfected with either sh-H19 or sh-NC (negative control). A qRT-PCR analysis demonstrated the expression levels of lncRNA H19 in cells. B Cell viability of Hela cells was assessed using a CCK-8 assay (OD450 nm). C Colony formation assay was conducted to assess the proliferative capacities of Hela cells. D Flow cytometry analysis was performed to detect the level of apoptosis in Hela cells. E Scratch wound healing assay was conducted to evaluate the migratory abilities of Hela cells (scale bar: 50 μm). F Transwell assay was performed to determine the invasive abilities of Hela cells (scale bar: 50 μm). G Western blotting was employed to explore the expression levels of apoptosis related proteins Bcl-2 and Bax in Hela cells. ** P < 0.01 compared to the sh-NC group