Table 3 Computed tomographic features of COVID-19-related ARDS versus non–COVID-19 ARDS
CT features | COVID-19 | Non–COVID-19 | p value |
|---|---|---|---|
(n = 32) | (n = 116) | ||
Time from ARDS onset to CT (days) | 1 (1–3) | 1 (1–4) | 0.876 |
Distribution of the lesions | |||
Peripheral only | 6 (18.8%) | 0 | |
Central only | 0 | 1 (0.9%) | |
Peripheral and central | 26 (81.3%) | 115 (99.1%) | < 0.001 |
Features | |||
GGO | 27 (84.4%) | 76 (65.5%) | 0.040 |
Consolidation | 26 (81.3%) | 109 (94%) | 0.024 |
Reticulation | 9 (28.1%) | 45 (38.8%) | 0.267 |
Crazy-paving | 5 (15.6%) | 18 (15.5%) | 0.988 |
Air bronchogram | 20 (62.5%) | 109 (94%) | < 0.001 |
Pleural effusion | 7 (21.9%) | 89 (76.7%) | < 0.001 |
Pleural thickening | 0 | 4 (3.4%) | |
Subpleural sparing | 1 (3.1%) | 2 (1.7%) | 0.521 |
Pulmonary embolism | 4 (12.5%) | 0 | |
Lymphadenopathy | 17 (53.1%) | 60 (51.7%) | 0.888 |
Pulmonary nodules | 2 (6.3%) | 15 (12.9%) | 0.367 |
Cavity | 0 | 6 (5.2%) | |
Main patterns | |||
GGO | 20 (62.5%) | 17 (14.7%) | < 0.001 |
Consolidation | 10 (31.3%) | 87 (75%) | < 0.001 |
Crazy-paving | 2 (6.3%) | 12 (10.3%) | 0.735 |
Ventilation | |||
Overinflation | 3 (9.4%) | 12 (10.3%) | 1.000 |
Normal ventilation | 22 (68.8%) | 20 (17.2%) | < 0.001 |
Collapse | 7 (21.9%) | 84 (72.4%) | < 0.001 |
CT severity score | |||
Right upper lobe | 2.4 ± 1.5 | 3.3 ± 1.5 | 0.004 |
Right middle lobe | 2.5 ± 1.1 | 3.2 ± 1.3 | 0.004 |
Right lower lobe | 3.2 ± 1.2 | 4.1 ± 1.1 | < 0.001 |
Left upper lobe | 2.4 ± 1.1 | 3.3 ± 1.3 | < 0.001 |
Left lower lobe | 3.1 ± 1.2 | 4.1 ± 1.1 | < 0.001 |
Total score | 10.5 ± 3.7 | 18.0 ± 4.6 | < 0.001 |