Table 1 Anthropometric and clinical characteristics of IgAN patients categorized by quartile of TyG–BMI

Age (years)

39.37 ± 10.92

32.91 ± 9.09

41.00 ± 11.25^‡

42.68 ± 10.60^‡

40.91 ± 10.06^‡

Gender (Males n,%)

173 (52.91)

25 (30.49)

47 (57.32)^‡

47 (57.32)^‡

54 (66.67)^‡

Height (m)

1.64 ± 0.08

1.63 ± 0.07

1.64 ± 0.09

1.64 ± 0.08

1.65 ± 0.08

Weight (kg)

65.38 ± 15.15

51.99 ± 6.31

61.36 ± 7.59^‡

68.19 ± 6.96^‡

80.18 ± 18.91^‡

BMI (kg/m²)

24.24 ± 5.02

19.49 ± 1.58

22.83 ± 1.32^‡

25.18 ± 0.98^‡

29.52 ± 6.55^‡

Smoking (n, %)

19 (5.81)

2 (2.44)

3 (3.66)

6 (7.31)

8 (9.88)^†

Alcohol use (n, %)

9 (2.75)

1 (1.22)

0 (0)

3 (3.66)

5 (6.17)

SBP (mmHg)

128.44 ± 19.35

118.71 ± 16.18

129.88 ± 22.29^‡

131.24 ± 16.86^‡

134.01 ± 18.18^‡

DBP (mmHg)

85.81 ± 13.42

79.99 ± 10.85

87.18 ± 16.86^‡

88.48 ± 11.06^‡

87.61 ± 12.47^‡

RAS blocking agents (n,%)

45(13.76)

5 (6.10)

10 (12.20)

17 (20.73)^‡

13 (16.05)^†

Hemoglobin (g/l)

131.78 ± 19.61

126.87 ± 17.57

134.5 ± 19.54^‡

131.26 ± 21.47

134.52 ± 18.98^‡

CRP

0.96 (0.07–3.31)

1.57 (0.07–5.36)

0.42 (0.07–2.25)^†

2.18 (0.18–3.81)

0.32 (0.07–1.95)^†

PCR

897.49 (365.11–1882.65)

926.58 (341.02–2092.44)

715.47 (350.01–1631.53)

1017.26 (415.15–1918.61)

936.62 (402.07–1953.22)

ACR

500.55 (212.30–1113.60)

518.76 (186.08–1155.78)

422.10 (201.77–1020.03)

545.59 (228.09–1116.13)

530.89 (204.05–1178.53)

Triglyceride (mg/dl)

1.74 ± 1.42

0.95 ± 0.42

1.35 ± 0.68^‡

1.70 ± 0.58^‡

2.98 ± 2.20^‡

Total cholesterol (mg/dl)

4.78 ± 1.31

4.82 ± 1.05

4.70 ± 1.27

4.55 ± 1.52

5.06 ± 1.33

LDL-C (mg/dl)

2.81 ± 1.14

2.79 ± 0.91

2.73 ± 1.13

2.77 ± 1.42

2.93 ± 1.07

HDL-C (mg/dl)

1.19 ± 0.39

1.24 ± 0.41

1.20 ± 0.51

1.12 ± 0.31^†

1.20 ± 0.32

TyG index

8.44 ± 0.62

7.92 ± 0.39

8.27 ± 0.44^‡

8.56 ± 0.37^‡

9.02 ± 0.64^‡

Serum creatinine (mg/dl)

90.00 (69.00–125.00)

75.68 (57.15–94.58)

98.75 (74.28–143.00)^‡

92.50 (72.73–133.25)^‡

101.00 (79.00–135.00)^‡

Uric acid (mg/dl)

395.78 ± 105.64

347.43 ± 87.29

399.01 ± 110.58^‡

403.04 ± 104.69^‡

434.10 ± 101.67^‡

Urea nitrogen (mg/dl)

6.02 ± 3.05

4.92 ± 1.94

6.40 ± 3.19^‡

6.27 ± 3.54^‡

6.50 ± 3.07^‡

eGFR (ml/min/1.73 m²)

80.36 ± 32.00

98.02 ± 27.80

74.60 ± 31.19^‡

75.97 ± 31.03^‡

72.77 ± 31.60^‡

LVM (g)

142.42 ± 39.64

114.17 ± 27.68

141.82 ± 38.23^‡

146.66 ± 31.70^‡

167.33 ± 40.79^‡

LVMI (g/m^2.7)

37.34 ± 9.38

30.41 ± 6.75

37.32 ± 8.91^‡

38.26 ± 7.55^‡

43.45 ± 9.32^‡

LVH (n, %)

44 (13.46)

2 (2.44)

9 (10.98)^†

9 (10.98)^†

24 (29.63)^‡

UTP

1101.82 (491.00–2361.12)

1162.44 (478.91–2685.15)

892.80 (454.66–2056.86)

781.23 (385.22–1646.65)

573.00 (243.33–1293.73)

Urinary sodium (mmol/L)

68.97 ± 32.35

68.16 ± 31.85

67.04 ± 28.53

74.37 ± 38.95

66.26 ± 28.90

Urinary potassium (mmol/L)

17.71 ± 7.94

17.88 ± 8.46

17.02 ± 7.17

18.09 ± 7.91

17.83 ± 8.25

Serum sodium(mmol/L)

140.93 ± 2.22

140.38 ± 2.34

141.16 ± 2.37^†

141.15 ± 1.76^†

141.02 ± 2.32

Serum potassium (mmol/L)

3.74 ± 0.39

3.65 ± 0.30

3.77 ± 0.43^†

3.78 ± 0.37^†

3.78 ± 0.43^†