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Table 3 Spearman correlation coefficient between 25-OHD3 metabolites and CKD severity in DM patients

From: Differential seasonal performance of C3-epi-D3 level and proportion on multiple metabolic disorders in patients with type 2 diabetes mellitus

Seasons

25-OHD3 level

C3-epi-D3 level

%C3-epi-D3

ρ (95%CI)

P

ρ (95%CI)

P

ρ (95%CI)

P

CKD severity

 All season (n = 1222)

− 0.227 (− 0.279, − 0.173)

 0.001

0.111 (0.055, 0.166)

< 0.001

0.230 (0.176, 0.283)

< 0.001

 Spring (n = 237)

− 0.151 (− 0.274, − 0.025)

0.020

0.016 (− 0.112, 0.143)

0.808

0.104 (− 0.024, 0.229)

0.109

 Summer (n = 340)

− 0.198 (− 0.298, − 0.093)

< 0.001

0.344 (0.246, 0.434)

< 0.001

0.445 (0.356, 0.527)

< 0.001

 Autumn (n = 350)

− 0.226 (− 0.323, − 0.124)

< 0.001

− 0.003 (− 0.107, 0.102)

0.960

0.113 (0.009, 0.216)

0.034

 Winter (n = 295)

− 0.208 (− 0.315, − 0.096)

< 0.001

− 0.027 (− 0.141, 0.088)

0.647

0.092 (− 0.022, 0.204)

0.114

Ca-IP

 All season (n = 591)

− 0.089 (− 0.169, − 0.009)

0.030

− 0.161 (− 0.239, − 0.082)

< 0.001

− 0.098 (− 0.177, − 0.018)

0.017

 Spring (n = 119)

− 0.048 (− 0.226, 0.133)

0.606

− 0.065 (− 0.242, 0.116)

0.482

− 0.033 (− 0.212, 0.148)

0.719

 Summer (n = 168)

− 0.046 (− 0.196, 0.106)

0.555

− 0.072 (− 0.221, 0.080)

0.352

− 0.042 (− 0.193, 0.110)

0.585

 Autumn (n = 166)

− 0.101 (− 0.250, 0.052)

0.194

− 0.336 (− 0.465, − 0.194)

< 0.001

− 0.245 (− 0.383, − 0.097)

0.001

 Winter (n = 138)

− 0.166 (− 0.324, 0.002)

0.052

− 0.304 (− 0.440, − 0.132)

< 0.001

− 0.120 (− 0.281, − 0.048)

0.161

Dyslipidemias

 All season (n = 1222)

− 0.018 (− 0.074, 0.038)

0.523

− 0.060 (− 0.116, − 0.004)

0.034

− 0.058 (− 0.113, − 0.001)

0.045

 Spring (n = 237)

− 0.166 (− 0.287, − 0.039)

0.011

− 0.149 (− 0.271, − 0.022)

0.022

− 0.100 (− 0.225, 0.028)

0.124

 Summer (n = 340)

− 0.009 (− 0.115, 0.098)

0.869

− 0.073 (− 0.178, 0.034)

0.179

− 0.047 (− 0.153, 0.060)

0.387

 Autumn (n = 350)

0.036 (− 0.069, 0.140)

0.504

0.035 (− 0.070, 0.140)

0.511

− 0.025 (− 0.129, 0.080)

0.641

 Winter (n = 295)

− 0.030 (− 0.085, 0.143)

0.613

− 0.094 (− 0.206, 0.021)

0.109

− 0.098 (− 0.210, 0.017)

0.094

  1. Based upon |ρ|≥ 0.3 considered as evident correlation [30], the results revealed that during specific season, there was a credible correlation between %C3-epi-D3 and CKD severity, as well as between C3-epi-D3 level and Ca-IP. Evident correlations are in bold
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European Journal of Medical Research

ISSN: 2047-783X

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