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Table 2 Comparison of laboratory results among patients with different severity of CKD

From: Differential seasonal performance of C3-epi-D3 level and proportion on multiple metabolic disorders in patients with type 2 diabetes mellitus

Indicator

Mild CKD

Moderate CKD

Serious CKD

χ2

P

n

M (P25, P75)

n

M (P25, P75)

n

M (P25, P75)

Male/female (n/n)

775

482/293

204

121/83

243

132/111

4.854

0.088

Age (years)

775

56 (50, 66)

204

64 (55, 73) ▲

243

65 (56, 76) ▲

92.458

< 0.001

25-OHD2 (ng/ml)

775

1.07 (0.71, 1.65)

204

1.05 (0.75, 1.75)

243

1.05 (0.68, 1.58)

1.601

0.449

25-OHD3 (ng/ml)

775

19.27 (14.58, 24.98)

204

16.14 (13.19, 20.73) ▲

243

15.72 (11.24, 21.49) ▲

62.173

< 0.001

C3-epi-D3 (ng/ml)

775

0.61 (0.42, 0.93)

204

0.62 (0.36, 0.99)

243

0.86 (0.41, 1.44) ▲

24.404

< 0.001

%C3-epi-D3 (%)

775

3.11 (2.24, 4.52)

204

3.36 (2.55, 5.57) ▲

243

5.82 (2.40, 9.37) ▲☺

72.218

< 0.001

Total protein (g/l)

775

72.6 (68.0, 76.5)

204

70.7 (65.0, 74.5) ▲

243

69.0 (63.1, 74.2) ▲

39.096

< 0.001

Albumin (g/l)

775

45.4 (42.7, 48.0)

204

43.1 (39.7, 46.3) ▲

243

41.8 (37.9, 45.9) ▲☺

95.657

< 0.001

Urea (mmol/l)

775

5.83 (4.75, 8.46)

204

7.33 (5.31, 10.12) ▲

243

8.55 (6.28, 12.72) ▲☺

73.069

< 0.001

SCr (μmol/l)

775

60.7 (42.3, 71.3)

204

58.1 (37.8, 82.5) ▲

243

71.0 (51.3, 107.8) ▲☺

53.559

< 0.001

CysC (mg/l)

775

0.95 (0.83, 1.08)

204

1.08 (0.89, 1.29) ▲

243

1.31 (1.03, 1.70) ▲☺

237.729

< 0.001

eGFR (ml/min/1.73m2)

775

95.8 (81.5, 116.5)

204

86.2 (61.9, 112.7) ▲

243

65.5 (45.1, 93.7) ▲☺

159.784

< 0.001

Triglyceride (mmol/l)

775

1.79 (1.20, 3.02)

204

1.63 (1.17, 2.49) ▲

243

1.66 (1.22, 2.32)

6.263

0.044

Total-Chol (mmol/l)

775

4.94 (4.14, 5.72)

204

5.06 (4.03, 6.06)

243

4.99 (3.87, 5.90)

0.702

0.704

LDL-Chol (mmol/l)

775

2.92 (2.30, 3.51)

204

2.97 (2.36, 3.97)

243

2.76 (2.07, 3.84)

3.948

0.139

HDL-Chol (mmol/l)

775

1.16 (0.97, 1.44)

204

1.17 (1.00, 1.44)

243

1.21 (1.01, 1.42)

2.151

0.341

Total calcium (mmol/l)

287

2.31 (2.20, 2.41)

153

2.32 (2.19, 2.42)

151

2.26 (2.15, 2.43)

3.829

0.147

Inorganic phosphorus (mmol/l)

287

1.09 (0.98, 1.22)

153

1.10 (1.01, 1.25)

151

1.17 (1.00, 1.29) ▲

8.258

0.016

Ca-IP [(mg/dl)2]

287

31.3 (27.8, 35.1)

153

31.8 (27.4, 36.7)

151

32.6 (27.8, 37.5)

2.817

0.245

UACR (mg/gCr)

775

9.2 (5.6, 13.8)

204

47.4 (30.5, 128.3) ▲

243

224.8 (35.3, 631.0) ▲

581.430

< 0.001

  1. Ca-IP calcium-phosphorus product. *▲ vs. mild CKD, Padj < 0.05; ☺ vs. moderate CKD, Padj < 0.05
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European Journal of Medical Research

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