Does T1c–2N0–1M0 triple negative breast cancer derive a benefit from neoadjuvant chemotherapy?

Table 1 Baseline characteristics of patients with neoadjuvant chemotherapy and adjuvant chemotherapy

Characteristics		Neoadjuvant chemotherapy (n = 1183)		Adjuvant chemotherapy (n = 2550)		Total (n = 3733)		P^c
Characteristics		No	%	No	%	No	%	P^c
Age (years)	20–49	483	40.8	628	24.6	1111	29.8	< 0.001
Age (years)	50–79	700	59.2	1922	75.4	2622	70.2
Race	White	861	72.8	1772	69.5	2633	70.5	0.122
	Black	215	18.2	521	20.4	736	19.7
	Other^a	107	9.0	257	10.1	364	9.8
Marital status	Married	687	58.1	1461	57.3	2148	57.5	0.587
	Not married^b	455	38.5	983	38.5	1438	38.5
	Other/unknown	41	3.5	106	4.2	147	3.9
Grade	I and II	153	12.9	332	13.0	485	13.0	< 0.001
	III and IV	995	84.1	2202	86.4	3197	85.6
	Unknown	35	3.0	16	0.6	51	1.4
Laterality	Left	605	51.1	1295	50.8	1900	50.9	0.839
Laterality	Right	578	48.9	1255	49.2	1833	49.1
Tumor status	T1c	264	22.3	1355	53.1	1619	43.4	< 0.001
Tumor status	T2	919	77.7	1195	46.9	2114	56.6
Nodal status	N0	829	70.1	2051	80.4	2880	77.1	< 0.001
Nodal status	N1	354	29.9	499	19.6	853	22.9
Surgery approach	BCS	598	50.5	1561	61.2	2159	57.8	< 0.001
Surgery approach	Mastectomy	585	49.5	989	38.8	1574	42.2
Radiation status	No	523	44.2	1071	42.0	1594	42.7	0.204
Radiation status	Yes	660	55.8	1479	58.0	2139	57.3

BCS breast-conserving surgery
^aOther includes American Indian/Alaskan native and Asian/Pacific Islander and Unknown
^bNot married includes divorced, separated, single (never married), unmarried or domestic partner, and widowed
^cThe p value of the chi-square test was calculated between the neoadjuvant chemotherapy and adjuvant chemotherapy groups, and bold type indicates significance

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