Figure 2

Change in total cholesterol and LDL from baseline to week 48 (ITT, LOCF): (a) median change (IQR) in total cholesterol and LDL, stratified according to baseline level; (b) changes in total cholesterol stratified by Grade. Baseline strata. Normal: Total cholesterol < 200 mg/dL; LDL < 130 mg/dL. Grade I-II: Total cholesterol 200-300 mg/dL; LDL 130-190 mg/dL. Grade III-IV: Total cholesterol > 300 mg/dL; LDL > 190 mg/dL.